This study aimed to compare the bioactive compounds in Centella
asiatica (C. asiatica) cultivated in a smart farm
and a field and their effects on human keratinocyte cells. C.
asiatica was collected in Jeju-do, Korea, and cultured in a smart
farm and a field. The main bioactive compounds in the two differentially
cultured C. asiatica were identified, and their activation in
keratinocytes were assessed. Amplification and sequencing of the internal
transcribed spacer (ITS) DNA in the nucleus and psbA-H DNA in
the chloroplast were performed for species analysis. A comparison of DNA of
plants reported in the NCBI GenBank was performed. The ITS DNA and
psbA-H DNA sequences of C. asiatica
cultivated in a smart farm and a field were consistent with No.
MH768338.1 and No. JQ425422.1, respectively. Analysis of the triterpenes was
performed using high performance liquid chromatography (HPLC) and as a result,
C. asiatica cultured in a smart farm had more triterpenes
than those cultured in a field. The effects of C. asiatica
grown in a smart farm on cell proliferation and scratch recovery in HaCaT cells
were greater than those grown in a field. These results suggest that C.
asiatica cultivated in a smart farm can be effectively utilized as
a health functional food.
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