Rhabdomyosarcoma is a malignant tumor of striated muscle tissue that can exceptionally present in the pleura. Its prognosis is generally poor. We report a case of an eight-year-old child admitted for a persistent dry cough which had progressed for three weeks, complicated by breathing difficulties and a deterioration in general condition. He had a history of recent contact with an uncle with pulmonary tuberculosis. Clinical examination on admission revealed right pleural effusion syndrome with moderate respiratory repercussion. The biological assessment shows moderate inflammation and a very high level of lactate dehydrogenase (LDH). Radiologically, there was abundant right pleurisy with intra-pleural nodular masses without ipsilateral pulmonary invasion or other distant localization. Pleural puncture reveals exudative lymphocytic fluid with negative tuberculous polymerase chain reaction (PCR) and atypical cells in cytology. Biopsy of the pleural mass showed pleural rhabdomyosarcoma of the alveolar type. The pet scan found bone metastases at two costal arches. After conditioning, the child received several courses of chemotherapy. The clinical and radiological outcome was favorable. This case is reported in view of its rarity and originality. We conclude that early diagnosis and treatment greatly improves the prognosis of this aggressive tumor.

Cup Like acute myeloid leukemia is the rarest form of children leukemia. We present a case of Cup Like Acute Myeloid Leukemia (AML) with t(4;12) (q12;p13) associated with two other clones t(1;16)(q12;q24) and t(12;13)(p13;q13). Cytogenetic and iFISH are highly relevant for the prognosis of and therapeutic decisions in LAM.

Childhood liver tumors are rare, but two-thirds are of malignant origin. Basically, before the age of 3, the main diagnoses are Hepatoblastoma (HB) and hemangioma. Infantile Hepatic Hemangioma (HHI) is a subclass of infantile hemangiomas that are the most common self-limiting benign tumors of early childhood. Only the diffuse forms or associated with congestive heart failure can be fatal. Careful clinical examination associated with biological and radiological elements does not always allow a diagnosis to be made. The biopsy is still performed frequently for diagnostic or prognostic purposes. Because of the diagnostic difficulties with HB, and the severity of some forms of HHI, we report the case of a newborn with diffuse HHI, observed at the Cheikh Khalifa International University Hospital in Casablanca. This was a newborn male in whom symptomatology of the disease consisted of increased abdominal volume, hepatomegaly and signs of respiratory struggle. The ultrasound described the existence of a multi-hetero-nodular hepatomegaly, and the CT scan a liver increased in size, seat of a large mass, poorly limited with bumpy contours of predominant tissue density with individualization of a central area of fluid density necrosis, containing calcifications. The AFP rate was high. An ultrasound-guided percutaneous biopsy confirmed the diagnosis of HHI. The course was very rapid and fatal in this patient with diffuse HHI with congestive heart failure.