Background:
The impact of gestational diabetes mellitus GDM is severe since it is directly associated with the detrimental intra-uterine environment, which may lead to enhanced risk of development of fetal metabolic disorders and affects mother and offspring both. Plant derived polyphenols are reported for their protective roles against a variety of human diseases; however, the impact of adherence to polyphenols on the risk of GDM has not been exhaustively reviewed.
Objective:
Aim of this review is to summarize relevant studies linking polyphenols and polyphenol rich dietary patterns by carefully considering the mechanisms of their action to the risk of GDM and its management.
Method:
Data from PubMed, ScienceDirect, and Springer online databases and updates from the Indian Council of Medical Research (ICMR) were studied.
Conclusion:
Present review provides a comprehensive report on the association between plant polyphenols and lower risk of GDM, suggesting that polyphenol-rich dietary patterns may be important in preventing the development of GDM and its healthy management.
Objective: The objective of the study is to assess protein oxidation status and its correlation with antioxidant potential in serum during preeclampsia (PE). Materials and Methods: A casecontrol study was performed on 63 pregnant subjects (mean age = 30 tential in serpreeclamptic and 32 age-matched normotensive (control) pregnant women. Serum samples were analyzed for total protein, globulin, albumin, protein carbonyls (PCO), advanced oxidation protein products (AOPP), and ferric reducing antioxidant potential. Results: Compared to the control pregnant subjects, a compromised serum protein pattern, elevated PCO (P < 0.01), and AOPP (P < 0.02) were observed in PE pregnant women that were correlated significantly with the total antioxidant potential of serum. Conclusion: The results of the study suggest that PE pregnancies are susceptible to protein oxidation which may be due to diminished antioxidant potential during PE. The study concludes that oxidative modulation of proteins may be one of the major causative factors in complicating the maternal and fetal conditions during PE.
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