Removing pixel-wise heterogeneous motion blur is challenging due to the ill-posed nature of the problem. The predominant solution is to estimate the blur kernel by adding a prior, but the extensive literature on the subject indicates the difficulty in identifying a prior which is suitably informative, and general. Rather than imposing a prior based on theory, we propose instead to learn one from the data. Learning a prior over the latent image would require modeling all possible image content. The critical observation underpinning our approach is thus that learning the motion flow instead allows the model to focus on the cause of the blur, irrespective of the image content. This is a much easier learning task, but it also avoids the iterative process through which latent image priors are typically applied. Our approach directly estimates the motion flow from the blurred image through a fully-convolutional deep neural network (FCN) and recovers the unblurred image from the estimated motion flow. Our FCN is the first universal end-to-end mapping from the blurred image to the dense motion flow. To train the FCN, we simulate motion flows to generate synthetic blurred-image-motion-flow pairs thus avoiding the need for human labeling. Extensive experiments on challenging realistic blurred images demonstrate that the proposed method outperforms the state-of-the-art.
This paper addresses issues of brain tumor subtype classification using Magnetic Resonance Images (MRIs) from different scanner modalities like T1 weighted, T1 weighted with contrast-enhanced, T2 weighted and FLAIR images. Currently most available glioma datasets are relatively moderate in size, and often accompanied with incomplete MRIs in different modalities. To tackle the commonly encountered problems of insufficiently large brain tumor datasets and incomplete modality of image for deep learning, we propose to add augmented brain MR images to enlarge the training dataset by employing a pairwise Generative Adversarial Network (GAN) model. The pairwise GAN is able to generate synthetic MRIs across different modalities. To achieve the patient-level diagnostic result, we propose a post-processing strategy to combine the slice-level glioma subtype classification results by majority voting. A two-stage course-tofine training strategy is proposed to learn the glioma feature using GAN-augmented MRIs followed by real MRIs. To evaluate the effectiveness of the proposed scheme, experiments have been conducted on a brain tumor dataset for classifying glioma molecular subtypes: isocitrate dehydrogenase 1 (IDH1) mutation and IDH1 wild-type. Our results on the dataset have shown good performance (with test accuracy 88.82%). Comparisons with several state-of-the-art methods are also included. INDEX TERMS Molecular-based brain tumor subtype classification, glioma, multi-modal, MRI, data augmentation, generative adversarial networks, deep learning.
This paper develops a multi-task learning framework that attempts to incorporate the image structure knowledge to assist image inpainting, which is not well explored in previous works. The primary idea is to train a shared generator to simultaneously complete the corrupted image and corresponding structures -edge and gradient, thus implicitly encouraging the generator to exploit relevant structure knowledge while inpainting. In the meantime, we also introduce a structure embedding scheme to explicitly embed the learned structure features into the inpainting process, thus to provide possible preconditions for image completion. Specifically, a novel pyramid structure loss is proposed to supervise structure learning and embedding. Moreover, an attention mechanism is developed to further exploit the recurrent structures and patterns in the image to refine the generated structures and contents. Through multi-task learning, structure embedding besides with attention, our framework takes advantage of the structure knowledge and outperforms several state-of-theart methods on benchmark datasets quantitatively and qualitatively.
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