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Accurate grading of skin disease severity plays a crucial role in precise treatment for patients. Acne vulgaris, the most common skin disease in adolescence, can be graded by evidence-based lesion counting as well as experiencebased global estimation in the medical field. However, due to the appearance similarity of acne with close severity, it is challenging to count and grade acne accurately. In this paper, we address the problem of acne image analysis via Label Distribution Learning (LDL) considering the ambiguous information among acne severity. Based on the professional grading criterion, we generate two acne label distributions considering the relationship between the similar number of lesions and severity of acne, respectively. We also propose a unified framework for joint acne image grading and counting, which is optimized by the multi-task learning loss. In addition, we further build the ACNE04 dataset with annotations of acne severity and lesion number of each image for evaluation. Experiments demonstrate that our proposed framework performs favorably against stateof-the-art methods. We make the code and dataset publicly available at https://github.com/xpwu95/ldl.

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The skin is the largest organ in human body. Around 30%-70% of individuals worldwide have skin related health problems, for whom effective and efficient diagnosis is necessary. Recently, computer aided diagnosis (CAD) systems have been successfully applied to the recognition of skin cancers in dermatoscopic images. However, little work has concentrated on the commonly encountered skin diseases in clinical images captured by easily-accessed cameras or mobile phones. Meanwhile, for a CAD system, the representations of skin lesions are required to be understandable for dermatologists so that the predictions are convincing. To address this problem, we present effective representations inspired by the accepted dermatological criteria for diagnosing clinical skin lesions. We demonstrate that the dermatological criteria are highly correlated with measurable visual components. Accordingly, we design six medical representations considering different criteria for the recognition of skin lesions, and construct a diagnosis system for clinical skin disease images. Experimental results show that the proposed medical representations can not only capture the manifestations of skin lesions effectively, and consistently with the dermatological criteria, but also improve the prediction performance with respect to the state-of-the-art methods based on uninterpretable features.

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Class imbalance is a challenging problem in many classification tasks. It induces biased classification results for minority classes which contain less training samples than others. Most existing approaches aim to remedy the imbalanced number of instances among categories by re-sampling the majority and minority classes accordingly. However, the imbalanced level of difficulty of recognizing different categories is also crucial, especially for distinguishing samples with many classes. For example, in the task of clinical skin disease recognition, several rare diseases have a small number of training samples, but they are easy to diagnose because of their distinct visual properties. On the other hand, some common skin diseases, e.g., eczema, are hard to recognize due to the lack of special symptoms. To address this problem, we propose a self-paced balance learning (SPBL) algorithm in this paper. Specifically, we introduce a comprehensive metric termed the complexity of image category which is a combination of both sample number and recognition difficulty. First, the complexity is initialized using the model of the first pace, where the pace indicates one iteration in the selfpaced learning paradigm. We then assign each class a penalty weight which is larger for more complex categories and smaller for easier ones, after which the curriculum is reconstructed by rearranging the training samples. Consequently, the model can iteratively learn discriminative representations via balancing the complexity in each pace. Experimental results on the SD-198 and SD-260 benchmark datasets demonstrate that the proposed SPBL algorithm performs favorably against the state-of-the-art methods. We also demonstrate the effectiveness of the SPBL algorithm's generalization capacity on various tasks such as indoor scene image recognition, object classification, etc.

Finding the informative subspaces of high-dimensional datasets is at the core of numerous applications in computer vision, where spectral-based subspace clustering is arguably the most widely studied method due to its strong empirical performance. Such algorithms first compute the affinity matrix to construct a self-representation for each sample using other samples as a dictionary. Sparsity and connectivity of the self-representation play important roles in effective subspace clustering. However, simultaneous optimization of both factors is difficult due to their conflicting nature, and most existing methods are designed to address only one factor. In this paper, we propose a post-processing technique to optimize both sparsity and connectivity by finding good neighbors. Good neighbors induce key connections among samples within a subspace and not only have large affinity coefficients but are also strongly connected to each other. We reassign the coefficients of the good neighbors and eliminate other entries to generate a new coefficient matrix. We show that the few good neighbors can effectively recover the subspace, and the proposed post-processing step of finding good neighbors can be complementary to most existing subspace clustering algorithms. Experiments on five benchmark datasets show that the proposed algorithm performs favorably against the state-of-the-art methods with negligible additional computation cost.