Accurate grading of skin disease severity plays a crucial role in precise treatment for patients. Acne vulgaris, the most common skin disease in adolescence, can be graded by evidence-based lesion counting as well as experiencebased global estimation in the medical field. However, due to the appearance similarity of acne with close severity, it is challenging to count and grade acne accurately. In this paper, we address the problem of acne image analysis via Label Distribution Learning (LDL) considering the ambiguous information among acne severity. Based on the professional grading criterion, we generate two acne label distributions considering the relationship between the similar number of lesions and severity of acne, respectively. We also propose a unified framework for joint acne image grading and counting, which is optimized by the multi-task learning loss. In addition, we further build the ACNE04 dataset with annotations of acne severity and lesion number of each image for evaluation. Experiments demonstrate that our proposed framework performs favorably against stateof-the-art methods. We make the code and dataset publicly available at https://github.com/xpwu95/ldl.

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The skin is the largest organ in human body. Around 30%-70% of individuals worldwide have skin related health problems, for whom effective and efficient diagnosis is necessary. Recently, computer aided diagnosis (CAD) systems have been successfully applied to the recognition of skin cancers in dermatoscopic images. However, little work has concentrated on the commonly encountered skin diseases in clinical images captured by easily-accessed cameras or mobile phones. Meanwhile, for a CAD system, the representations of skin lesions are required to be understandable for dermatologists so that the predictions are convincing. To address this problem, we present effective representations inspired by the accepted dermatological criteria for diagnosing clinical skin lesions. We demonstrate that the dermatological criteria are highly correlated with measurable visual components. Accordingly, we design six medical representations considering different criteria for the recognition of skin lesions, and construct a diagnosis system for clinical skin disease images. Experimental results show that the proposed medical representations can not only capture the manifestations of skin lesions effectively, and consistently with the dermatological criteria, but also improve the prediction performance with respect to the state-of-the-art methods based on uninterpretable features.

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