Endemic tick-borne relapsing fever (TBRF) has not been documented in Nigeria, yet clinically compatible cases have been described, and soft tick species are endemic in surrounding countries. Consequently, our aim was to investigate if TBRF-associated is present in Nigeria. To address this, we examined 49 soft tick pools to identify the tick species and to screen for The tick species was revealed by 16S rRNA gene amplification and Sanger sequencing to be , an aggressive, multihost, rapidly feeding species with significant veterinary impact. We detected a organism in 3 of 49 pooled samples (6%). Molecular analysis of amplified 16S rRNA and flagellin genes and intragenic spacer fragments disclosed that this organism was synonymous with the recently described organism " Borrelia kalaharica," identified in a tourist returning to Germany from South Africa. Given the widespread endemic range of this tick vector, TBRF should be considered part of the differential diagnosis for patients with fever returning from arid areas of Africa and further afield.
A cross sectional study using multistage sampling method by means of structured interviewer administered questionnaire was designed to estimate the rate of occurrence of needlestick injuries among veterinarians involved in clinical practice and to evaluate needle handling practices and risk factors. The study was carried out during the months of August–November 2015. Out of the 215 veterinarians that participated in the survey, 171 (79.5%) reported to have suffered needlestick injuries (NSIs). In the multivariable model, only male sex (OR 2.8, 95% CI 1.4–6.0, and P = 0.006) and working with poultry daily (OR 2.4, 95% CI 1.1–6.2, and P = 0.036) were significantly associated with NSI. Most (111, 64.9%) veterinarians had discomfort including pain, headache, fever, worry, and local numbness from NSIs; however, none was hospitalised. Only 1 (0.6%) had lost time at work. The approach to needlestick injury avoidance was poor and most (98.8%) NSIs were not reported. The findings of this research call for comprehensive health and injection safety programs for veterinarians involved in clinical practice.
B ats are vital to many ecosystems and provide benefits to humans (1). However, under certain circumstances, bats may pose a risk to human health, as they host several zoonotic pathogens (2). Humans should therefore avoid bat contact unless appropriate precautions are taken. Among the most concerning batborne pathogens are viruses within the genus Lyssavirus. Previously unimmunized humans exposed to any of the >16 currently recognized and putative lyssaviruses (typically through a bite from an infected animal) will have 1 of 3 outcomes. First is a complete lack of any lyssavirus infection, characterized by the absence of both illness and lyssavirus-neutralizing antibody production. Second is a productive lyssavirus infection, characterized by a fatal encephalitis known as rabies (3). A human with rabies may produce lyssavirus-neutralizing antibodies in the end stages of illness as the disease progresses, although this response is typically inadequate for viral clearance (4). Third is an abortive lyssavirus infection (sometimes termed an exposure) characterized by the absence of frank encephalitis but with production of lyssavirus-neutralizing antibodies. Although
This study examined the impact of armed conflict on public health surveillance systems, the limitations of traditional surveillance in this context, and innovative strategies to overcome these limitations. A qualitative case study was conducted to examine the factors affecting the functioning of poliovirus surveillance in conflict-affected areas of Borno state, Nigeria using semi-structured interviews of a purposeful sample of participants. The main inhibitors of surveillance were inaccessibility, the destroyed health infrastructure, and the destroyed communication network. These three challenges created a situation in which the traditional polio surveillance system could not function. Three strategies to overcome these challenges were viewed by respondents as the most impactful. First, local community informants were recruited to conduct surveillance for acute flaccid paralysis in children in the inaccessible areas. Second, the informants engaged in local-level negotiation with the insurgency groups to bring children with paralysis to accessible areas for investigation and sample collection. Third, GIS technology was used to track the places reached for surveillance and vaccination and to estimate the size and location of the inaccessible population. A modified monitoring system tracked tailored indicators including the number of places reached for surveillance and the number of acute flaccid paralysis cases detected and investigated, and utilized GIS technology to map the reach of the program. The surveillance strategies used in Borno were successful in increasing surveillance sensitivity in an area of protracted conflict and inaccessibility. This approach and some of the specific strategies may be useful in other areas of armed conflict.
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