Background The concept of transferring genes to tissues for clinical applications has been discussed for nearly half a century. The exponential increase in our ability to manipulate the genetic material of a cell via recombinant DNA technology has brought this goal closer to realization. The original perception that gene therapy should be considered only for a few major organs as a means of treating life-threatening disorders that are refractory to conventional treatment has changed. There are many non-life-threatening conditions that adversely affect a patient’s quality of life, for which there are no effective treatments. The lack of suitable treatment has permitted morbidity to become a rational basis for extending the scope of gene therapy. In the past few years, remarkable progress has been made in the field of gene therapy. While considerable problems remain, thus impeding the routine clinical use of gene transfer, gene therapy will have a pervasive and significant impact on areas that are based on biological science.Aim The purpose of this review is to examine the progress made in addressing gene transfer strategies for correcting various diseases and problems that are relevant to dental practice.
Back ground and objectives:Work activities in shipping port are known to be a physically demanding task. The risk of getting occupational related back pain among them is relatively high. Currently, there is limited data that can be used to determine the status of occupational related back pain among them in local setting. The aim of study is to evaluate the prevalence of occupational related back pain among shipping port workers. Methods:This is a cross sectional descriptive type of study. The respondents were shipping port workers receiving physiotherapy treatment for their occupational related back pain at the shipping medical center. A set of questionnaire were distributed to gather their demographic data and back pain pain intensity.Results:A total of 81 respondent eligible to this study with mean age of is 34.9 (±8.78), maximum pain intensity recorded was 5/10. Majority (n=59) of respondent seeking physiotherapy treatment were engaged with crane maneuver. The activity that increase the incidence of back pain is driving heavy vehicle (n=27) and adopting prolong trunk bending (n=20). There is no statistically significant (p>0.005) association between pain intensity, age, body mass index (BMI) and waist measurement. Conclusion:This study didn't investigate employees knowledge and their working habit at workplace. Such factors cannot be denied and should be investigated to determine its relationship with occupational related back pain. Subsequently, a constructive preventive measures should be tailored accordingly in order to curb occupational related back pain among shipping port workers.
Back ground of the study: As the adolescence grows the food habits also changes accordingly. Eating healthy food promotes good healthy development among the young citizen called youth. Physical, mental, emotional and social behaviors also get altered due to the junk food habit. This study was aimed to examine the extent which the youth seek junk food, reasons for this craving among youth, impact of junk food eating habit and to study the efforts made to respond the problem of obesity. Methodology: Exploratory research design with the aims to establish the most basic criteria of the research topic, often before the actual study was started. Convenient sampling method was used for different group of samples. Seventy (70) subjects were participated in the study. Samples selected from college students of 2 different cities in Chennai; Nungambakkam and Avadi. Validated questionnaire were used to find the outcome of the study. Result: Many responded that the junk food is a solid food it is clearly found with the ratio (65.71%), many finding were observed that the junk food culture and that changes in eating pattern. Conclusion: The complex and evolving nature of youth attitudes towards obesity prevention efforts and their understanding of the causes and consequences of obesity.
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