These results are consistent with the goal of endosomal destabilization of the carrier design. This method provides a quantitative means for assessing different polymer construct designs for gene delivery.

Because gene expression profiles are highly sensitive to sample and processing conditions, it is crucial to accurately represent these conditions along with the numeric data in a way that allows the conditions to be part of a query. The GeneX TM project is intended to provide an Open Source database and integrated tool set that will allow researchers to store and evaluate their gene expression data and, moreover, such evaluation will be independent of the technology used to obtain the data.

It was concluded that the unlabeled-probe HRM approach can be a sensitive and accurate screening technique to detect KRAS codon 12 and 13 mutations in diagnosing and treating PA.