Deep learning techniques have provided new research methods for computer-aided diagnosis, allowing researchers to use deep learning methods to process medical imaging data. Chest X-ray examinations are widely used as a primary screening method for chest diseases. Therefore, it is of great importance to study diagnosis of 14 common pathologies in chest X-ray images using deep learning methods. In this paper, we propose a deep learning model named AM_DenseNet for chest X-ray image classification. The model adopts a dense connection network and adds an attention module after each dense block to optimize the model’s ability to extract features, and finally a Focal Loss function is applied to solve the data imbalance problem. The experiments used chest X-ray images as model input and were trained to output the probabilities of 14 chest pathologies. The Area under the ROC curve (AUC) was used to measure the classification results, and the final average AUC was 0.8537. The experimental results show that the AM_DenseNet model could complete the pathology classification of the chest X-ray images effectively.
Multimodal medical images are useful for observing tissue structure clearly in clinical practice. To integrate multimodal information, multimodal registration is significant. The entropy-based registration applies a structure descriptor set to replace the original multimodal image and compute similarity to express the correlation of images. The accuracy and converging rate of the registration depend on this set. We propose a new method, logarithmic fuzzy entropy function, to compute the descriptor set. It is obvious that the proposed method can increase the upper bound value from log(r) to log(r) + ∆(r) so that a more representative structural descriptor set is formed. The experiment results show that our method has faster converging rate and wider quantified range in multimodal medical images registration.
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