The development of cracks in mining is the scientific basis for the safety and environmental exploitation of shallow multiple-seam. According to the “thickness of coal seam, interactive distance, and buried depth,” four mining coal mines are selected in Shen Fu-Dong Sheng coalfield (SFDSC). To research the mining conditions of shallow coal seam under different base-load ratio mining conditions and different working faces by the physics simulation and in-sit measurement, the key roof caves are sketched by different colors. This study shows that the typical shallow coal seams in the thin overlying bedrock and thick loose sand layer (LSL) as well as the development of the setup entry cracks (SEC) is dominated by LSL arch damage. The surface cracks are almost directly above the setup entry. The flat seam mining and the SEC development is dominated by parabolic type. The surface cracks are located inside the setup entry. With the mining height increased typically in a shallow coal seam, the rate of crack development and the extent of damaged area increased significantly. The SEC and boundary cracks are fixed. The dynamic periodic cracks (DPC) show the ability of the strata to self-repair. During the multiple-seam mining, the above three kinds of cracks have the phenomenon of activation and development. Through the reasonable coal pillar distance arrangement, the development of boundary cracks can be effectively controlled and the relatively uniform surface settlement and crack closure can be achieved. The purpose of reducing damage mining can also be achieved. Furthermore, it provides scientific support for the green mining in the shallow coal seam.

In order to explore the rational coal pillar malposition distance (CPMD) based on coupling control of stress field, displacement field and fracture field (three-field) in shallow buried closely spaced multi-seam (SBCSM-S) mining, and realize coupling control of underground concentrated stress and ground surface fractures, taking the No. 1–2 and No. 2–2 coal seams mining in the northward east area of Ningtiaota coal mine as background, through physical simulation and theoretical analysis, the three-field evolution in SBCSM-S mining was analysed, the effect of different CPMD on coal pillar concentrated stress, ground surface subsidence and fractures development was revealed, and the rational CPMD based on coupling control of three-field was put forward. The results show that the concentrated fractures and concentrated stress are due to the strata’s uneven subsidence by coal pillars. Rational arrangement of CPMD can avoid the superposition of vertical stress caused by upper and lower coal pillars and reduce the development of ground fractures and uneven subsidence. Two theoretical models were established: one was based on the control of a concentrated stress field, the other on the control of the displacement and fracture fields. These results will be applied in a follow-up arrangement at the Ningtiaota coal mine, and can provide a new way for safe and green mining in SBCSM-S.

When mechanized sub-horizontal section top coal caving (SSTCC) is used as an underground mining method for exploiting extremely steep and thick coal seams (ESTCS), a large-scale surrounding rock caving may be violently created and have the potential to induce asymmetric destabilization from mine voids. In this study, a methodology for assessing the destabilization was developed to simulate the Weihuliang coal mine in the Urumchi coal field, China. Coal-rock mass and geological structure characterization were integrated with rock mechanics testing for assessment of the methodology and factors influencing asymmetric destabilization. The porous rock-like composite material ensured accuracy for building a 3D geological physical model of mechanized SSTCC by combining multi-mean timely track monitoring including acoustic emission, crack optical acquirement, roof separation observation, and close-field photogrammetry. An asymmetric 3D modeling analysis for destabilization characteristics was completed. Data from the simulated hydraulic support and buried pressure sensor provided effective information that was linked with stress-strain relationship of the working face in ESTCS. The results of the 3D physical model experiments combined with hybrid statistical methods were effective for predicting dynamic hazards in ESTCS.

The fully mechanized mining with large mining height is the main method for high yield and efficient coal mining in China. The key stratum structure (KSS) is the basis of revealing the mechanism of roof weighting and determination of support working resistance of the longwall face with large mining height (LFLMH) in the shallow coal seam. The height of the caving zone at LFLMH is large, the thick immediate roof forms the “short cantilever beam” structure commonly, and the hinge layer of the overlying key stratum will move upward to the higher position. The “high position oblique step voussoir beam” structure of single-key stratum (SKS) and “oblique step voussoir beam and voussoir beam” structure of double-key stratum (DKS) in the shallow coal seam were proposed with physical simulation and Universal Distinct Element Code (UDEC). The analysis of the KSS and numerical simulation reveals the mechanism of strong roof weighting at the SKS longwall face and large-small alternate periodic weighting at the DKS longwall. It is concluded that the large static load caused by the “equivalent immediate roof (EIR)” is the basic load, and the instability load of the KSS is the additional dynamic load of support. Besides, the calculation methods of the reasonable support working resistance at LFLMH were obtained and verified with engineering applications.

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NUT (nuclear protein in testis) midline carcinoma is a rare malignant tumor arising in midline structures, such as head, neck and mediastinum. In the 2015 WHO classification of lung tumours, it was categorized in "Epithelial tumors". However, because of limited clinical data, its biological features have not been fully recognized. We report a case of NUT midline carcinoma presented as a primary lung tumor. Pneumonectomy was performed without any neoadjuvant therapy and it turned out to be a gross total resection. Even so, the prognosis is poor with a disease-free survival of 2 months and an overall survival of 6 months.

Immune checkpoint inhibitors (ICIs) have significantly improved outcomes for cancer patients.With the widespread clinical application of ICIs, their adverse reactions have gradually been recognized.The side effects of ICIs are generally less severe than those of chemotherapy. However, some adverse events with ICIs can be life-threatening. Fatal adverse events require a deep understanding and vigilance. Here, we report the case of a 69-year-old patient with esophagogastric junction carcinoma who experienced multiple immune-related adverse events, including Stevens-Johnson syndrome/toxic epidermal necrolysis, myositis, myocarditis, and liver toxicity, after receiving pembrolizumab. The patient experienced skin rash, bilateral ptosis, limb weakness, and shortness of breath. The symptoms progressed rapidly. Following treatment with methylprednisolone, intravenous immunoglobulin, and plasmapheresis, the patient recovered well.No tracheal intubation or tracheotomy was required owing to the timely and effective treatment. From this case, it can be seen that severe skin rash is an important indication of abnormal immune status and an early warning sign of subsequent multiple-organ involvement. As the most dangerous adverse event, myocarditis is closely related to the patient's prognosis. Severe irAEs appear early, progress rapidly, and involve multiple systems and organs, resulting in a high fatality rate. Early recognition and high-dose corticosteroids are key to successful treatment of such patients.

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