[1] Since the early 1980s, water management of rice paddies in China has changed substantially, with midseason drainage gradually replacing continuous flooding. This has provided an opportunity to estimate how a management alternative impacts greenhouse gas emissions at a large regional scale. We integrated a process-based model, DNDC, with a GIS database of paddy area, soil properties, and management factors. We simulated soil carbon sequestration (or net CO 2 emission) and CH 4 and N 2 O emissions from China's rice paddies (30 million ha), based on 1990 climate and management conditions, with two water management scenarios: continuous flooding and midseason drainage. The results indicated that this change in water management has reduced aggregate CH 4 emissions about 40%, or 5 Tg CH 4 yr À1 , roughly 5-10% of total global methane emissions from rice paddies. The mitigating effect of midseason drainage on CH 4 flux was highly uneven across the country; the highest flux reductions (>200 kg CH 4 -C ha À1 yr À1 ) were in Hainan, Sichuan, Hubei, and Guangdong provinces, with warmer weather and multiple-cropping rice systems. The smallest flux reductions (<25 kg CH 4 -C ha À1 yr À1 ) occurred in Tianjin, Hebei, Ningxia, Liaoning, and Gansu Provinces, with relatively cool weather and single cropping systems. Shifting water management from continuous flooding to midseason drainage increased N 2 O emissions from Chinese rice paddies by 0.15 Tg N yr À1 ($50% increase). This offset a large fraction of the greenhouse gas radiative forcing benefit gained by the decrease in CH 4 emissions. Midseason drainage-induced N 2 O fluxes were high (>8.0 kg N/ha) in Jilin, Liaoning, Heilongjiang, and Xinjiang provinces, where the paddy soils contained relatively high organic matter. Shifting water management from continuous flooding to midseason drainage reduced total net CO 2 emissions by 0.65 Tg CO 2 -C yr À1 , which made a relatively small contribution to the net climate impact due to the low radiative potential of CO 2 . The change in water management had very different effects on net greenhouse gas mitigation when implemented across climatic zones, soil types, or cropping systems. Maximum CH 4 reductions and minimum N 2 O increases were obtained when the mid-season draining was applied to rice paddies with warm weather, high soil clay content, and low soil organic matter content, for example, Sichuan, Hubei, Hunan, Guangdong, Guangxi, Anhui, and Jiangsu provinces, which have 60% of China's rice paddies and produce 65% of China's rice harvest.