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Hoh Xil is an uninhabited extremity secluded on the Tibetan Plateau hinterland. A complete mapping of ground motion variation in Hoh Xil is essential for in-depth understanding of terrain's responses to climate change on the Tibetan Plateau. However, the inaccessibility and extremely harsh environment impeded extensive field investigations on landform alteration and its formative process. Such difficulty can be resolved by Interferometric Synthetic Aperture Radar (InSAR), which enables a broad detection of subtle permafrost motions at millimeter precision. This study, for the first time, accomplished a Multi-temporal InSAR (MT-InSAR) deformation mapping from 2015 to 2020 in Hoh Xil, with a wide coverage of about 200,000 km 2 . 1,592 Sentinel-1 images were processed based on the small baseline subset (SBAS) technique. The results show that Hoh Xil was experiencing dynamic permafrost disturbances. Thawing permafrost with both the linear subsidence rate higher than 2 mm/yr and the periodic amplitude over 2 mm was primarily detected in areas of flat or gentle slopes. The InSAR cumulative deformation is highly correlated with permafrost thawing depth. Significant lag times were identified between seasonal oscillation of InSAR deformation and land surface temperature (LST). Thermokarst landforms of retrogressive thaw slumps and thermokarst lakes broadly formed and dynamically evolved as a consequence of permafrost degradation. Particularly, widespread thawing permafrost characterized by the spatial clustering of thermokarst lakes appeared to occur in areas adjacent to large lakes. The discovered dynamic permafrost disturbances in Hoh Xil manifested even the secluded Tibetan Plateau hinterland was facing the threat of climate change.

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