In this work, we demonstrate a simple, versatile, and real-time motion guidance strategy for artificial microengines and motile microorganisms in a ferrofluid by dynamic topographical pathways (DTPs), which are assembled from superparamagnetic nanoparticles in response to external magnetic field ( H). In this general strategy, the DTPs can exert anisotropic resistance forces on autonomously moving microengines and thus regulate their orientation. As the DTPs with different directions and lengths can be reversibly and swiftly assembled in response to the applied H, the microengines in the ferrofluid can be guided on demand with controlled motion directions and trajectories, including circular, elliptical, straight-line, semi-sine, and sinusoidal trajectories. The as-demonstrated control strategy obviates reliance on the customized responses of micromotors and applies to autonomously propelling agents swimming both in bulk and near substrate walls. Furthermore, the microengines (or motile microorganisms) in a ferrofluid can be considered as an integrated system, and it may inspire the development of intelligent systems with cooperative functions for biomedical and environmental applications.
Extraction of nucleic acids in microsystems is of significance for biomedical applications, but the current extraction methods generally require sophisticated microchannels and external equipment, hindering their practical applications. In this work, we have demonstrated a simple, versatile and efficient approach to extract nucleic acids in microsystems by developing cationic branched polyethyleneimine (PEI)‐functionalized tubular micromotors. The as‐developed tubular micromotors are fabricated by a two‐step process combining the template‐assisted electrodeposition and carbodiimide chemistry, and contain an inner catalytic Pt layer, a middle magnetic Ni layer and an outer cationic PEI layer. They exhibit autonomous bubble‐propelled motion in aqueous hydrogen peroxide solutions, which can be guided by an external magnetic field, and the surface charges can be reversibly modulated by changing the pH value of the solution. Consequently, the as‐developed tubular micromotors can selectively absorb nucleic acids from acidic solutions and desorb them into alkaline solutions, leading to the extraction of nucleic acids with high efficiency without external stirring. Furthermore, they can be operated in a microchannel chip without the aid of a pumping system. Our results indicate that this PEI‐functionalized tubular micromotor platform provides a novel, simple and versatile microsystem nucleic acid extraction technology, holding considerable promise for important practical applications.
An energetics analysis of fish self-propelled swimming SCIENCE CHINA Physics, Mechanics & Astronomy 61, 074721 (2018); Design and mesoscopic description of self-propelled nanomotor in complex environment Chinese Science Bulletin 62, 209 (62); Numerical simulations of self-propelled swimming of 3D bionic fish school Science in China Series E-Technological Sciences 52, 658 (2009); A study of a three-dimensional self-propelled flying bird with flapping wings
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