Although photodynamic therapy (PDT) has promising advantages in almost non‐invasion, low drug resistance, and low dark toxicity, it still suffers from limitations in the lipophilic nature of most photosensitizers (PSs), short half‐life of PS in plasma, poor tissue penetration, and low tumor specificity. To overcome these limitations and enhance PDT, liposomes, as excellent multi‐functional nano‐carriers for drug delivery, have been extensively studied in multi‐functional theranostics, including liposomal PS, targeted drug delivery, controllable drug release, image‐guided therapy, and combined therapy. This review provides researchers with a useful reference in liposome‐based drug delivery.
A highly efficient and regioselective bromination of electron-rich arenes and heteroarenes using commercially available BrCCl3 as a “Br” source has been developed. The reaction was performed in the air under...
This paper reported a catalyst‐ and metal‐free method to construct disulfide bond with BrCCl3 under light irradiation. This clean and mild reaction promoted the oxidative coupling of thiols with wide substrate scope, and is applicable to benzylic, aryl and aliphatic thiols, especially cysteine derivative. The disulfides were obtained in high yields up to 98 %, avoiding the use of heating, strong oxidant, metal reagent or catalyst. This facile strategy will facilitate the synthesis of disulfide compounds.
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