Wearable electronics are increasingly used in health monitoring and treatment in different conditions. However, few devices can adhere conformally to the skin after sports and showers (sweating, deformation, friction). Here, a facile method is presented by providing a metal‐polymer conductor (MPC) made with polyethylene glycol (PEG) blended polydimethylsiloxane (PDMS) based adhesive (PPA) that encapsulates gallium‐based liquid metal alloy circuits as epidermal electronics. Adding PEG into PDMS prepolymer can result in a softer and wet‐adhesive elastomer that can bear larger deformation than PDMS itself. The soft and adhesive electronics can adhere to the skin conformally for more than 2 d. It has been demonstrated that these electronics can meet the needs of motion detection, electrophysiological signal detection and skin wound healing during a 48 h wearing with sports and shower. It is expected that the wet‐adhesive electronic with excellent biosafety can be widely used and solve existing problems in medical adhesives and human–machine interfaces.
The potential toxicity of nanoplastics on plants has previously been illustrated, but whether nanoplastics could cause neurotoxicity, especially to higher animals, remains unclear. We now demonstrate that nanoplastics can be deposited in the brain via nasal inhalation, triggering neuron toxicity and altering the animal behavior. Polystyrene nanoparticles (PS-NPs) of PS-COOH and PS-NH 2 are used as models for nanoplastics. We designed a microfluidic chip to evaluate the PS-NPs with different concentrations, surface ligands, and sizes to interact with neurons. Smaller PS-NPs can induce more cellular uptake than larger PS-NPs. PS-NPs with a size of 80 nm can reach and deposit in the brain of mice via aerosol inhalation. Mice inhaling PS-NPs exhibit fewer activities in comparison to those inhaling water droplets. An obvious neurotoxicity of the nanoplastics could be observed from the results of the inhibition of AChE activities. Our results show the potential significance of the physiochemical properties of organic nanoplastics on depositing in mammalian brains by nasal inhalation.
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