Histologic conversion from a low-grade non-Hodgkin's lymphoma (NHL) into a more aggressive histologic pattern is a common, well-documented event in NHL. The converse phenomenon, appearance of a low-grade, follicular NHL after treatment for diffuse, intermediate, or high-grade NHL, has only recently been recognized. The clinical, morphologic, and immunologic features of a patient in whom relapse with an indolent nodular lymphoma was noticed after combination chemotherapy for diffuse lymphoma are presented. Immunologic markers at presentation and relapse were similar. Other previously reported cases are reviewed. Implications for diagnosis and therapy as well as the pathogenesis of this unique form of conversion are discussed.
Objetivo: Investigar el efecto de los extractos acuosos en infusión y cocimiento de unnutraceutico compuesto de Ocimum micranthum Willd (ISHCATUL®), en un modelo deulcera gástrica inducida con etanol en ratas. Materiales y Métodos: Estudioexperimental. Se distribuyeron 25 ratas machos en cuatro grupos de estudio: 1)Control Negativo (Suero fisiológico 0.9% 1mL/100 g); 2) Control Positivo (Sucralfato500 mg/Kg); 3) Experimental 1 (Cocimiento a dosis 1mL/100 g); y 4) Experimental 2(Infusión a dosis 2mL. /100 g). Adicionalmente se utilizó una rata como blanco, parapoder realizar comparaciones mediante la visualización directa del tejido gástrico. Seindujo ulcera gástrica mediante la administración intragastrica de Etanol absoluto al75% 1 mL/100g. Se realizó una observación directa de características macroscópicascon las que se calculó el índice ulceroso y porcentajes de inhibición de ulceragástrica. Resultados: El grupo de tratamiento 1 y 2 obtuvieron un porcentaje deinhibición de 35.2% y 21.2 %, lo que no fue superior comparado con el 75% obtenidopor el grupo que recibió sucralfato. Conclusión: Se encontraron efectosgastroprotectores en los grupos de estudio que recibieron decocto (a 1 mL/mg) einfusión (a 2mL/mg) de un nutraceutico compuesto de Ocimum micranthum Willd(Albahaca salvaje), en modelos experimentales de inducción de ulcera gástrica poretanol al 75%, que no fueron superiores a los controles positivos.
The treatment of corneal lesions continues to be a topic of great interest. However, despite the development of new technologies and due to the slow evolution and uncertain healing of corneal lesions, they still represent a public health problem since patients can be affected for life, affecting the family and the health system due to the costly and uncertain response to treatment. For this reason, the need arises to seek therapeutic alternatives to treat these patients.
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