Neurosurgeries have become more frequent in veterinary hospitals, however, there are some questions regarding anesthetics protocols and analgesic techniques. Thus, patient analgesia and hemodynamic stability play a key role in pre, post, and perioperative moments favoring an adequate recovery. This study aimed to evaluate the transanesthetic complications reported on anesthetic records of dogs submitted to hemilaminectomies in the university veterinary hospital of the Federal University of Santa Maria (UFSM) between January 2016 and August 2017, and compare three different analgesic protocols most commonly used in the routine for this surgery. In addition, transanesthetic parameters for each dog were equally recorded in five-minute intervals: cardiac frequency (FC), respiratory frequency (f) blood oxygen saturation (SpO2), mean artery pressure (PAM), temperature and end tidal CO2 (EtCO2). The patients were divided into three groups: Group M: animals receiving epidural analgesia with morphine 0.1mg/kg diluted in 0.26 ml/kg of saline solution 0.9%; Group FLK: bolus of fentanyl 2 μg/kg, lidocaine 1 mg/kg, and ketamine 1 mg/kg followed by infusion of fentanyl 0.1 μg/kg/min, lidocaine 50 μg/kg/min and ketamine 10 μg/ kg/min; and Group F: bolus of fentanyl 2 μg/kg followed by infusion of fentanyl 0.1 μg/kg/min. ANOVA was used to evaluate the anesthetic protocols complications, followed by Tukey’s post-hoc test with a significance level of 5% (p <0.05), comparing the mean of each parameter. Among the anesthetic complications that were found hypotension, bradycardia and hypercapnia were the most frequent. When 22.22% of the patients presented hypotension more evident on the first 10 minutes of anesthesia, 22.22% presented bradycardia, requiring the use of atropine (0.022 mg/kg) and 83.33% had hypercapnia on at least one of the times (EtCO2 > 45mmHg). With this study, it was observed that the use of continuous infusions of FLK, fentanyl, and epidural analgesia with morphine, in the used doses, were effective and safe in the dogs submitted to neurosurgeries, however, it was noticed that the use of morphine caused a greater reduction in temperature during the intraoperative period.
We investigated the local and systemic effects of hyperbaric oxygen therapy in BALB/C mice, exposed to two different exposure times, under 2.4 atmosphere (ATM). Fifteen animals were divided into three groups (GI, GII and Control) and underwent a surgical excision of a skin fragment of approximately one square centimeter of the dorsal region. The wounds were treated and monitored for 21 days. In the control group, the wound was cleaned once a day with sterile 0.9% NaCl solution. GI and GII mice were submitted to daily hyperbaric oxygen therapy of 30 or 60minutes sessions, respectively. The wounds were photographed every three days and their surfaces were analyzed by an image analyzer. At 21 days, all animals were euthanatized for histopathological analysis of the skin, lungs and liver in order to identify eventual alterations in wound healing or in the analyzed organs. Animals belonging to GI showed a faster skin wound healing in comparison to the other groups. Animals from GII, however, showed a delayed wound healing process and exhibited lung and microcirculatory alterations. These findings allow us to conclude that the exposure time to the oxygen in hyperbaric environment is crucial and can help or disturb skin wound healing or even be deleterious to other organs.
Resumo.A monitoração da função cardiorrespiratória é de extrema importância para o paciente anestesiado, atribuindo grande relevância a monitoração de pressão arterial. A pressão arterial média representa a condução da perfusão tecidual, sendo fundamental sua aferição para garantir uma anestesia segura. Pacientes neurológicos estão altamente suscetíveis a alterações hemodinâmicas durante procedimentos cirúrgicos como a hemilaminectomia e com isto, este trabalho levantou informações de fichas anestésicas de pacientes os quais realizaram esta cirurgia na Universidade Federal de Santa Maria no período de janeiro de 2016 a outubro de 2017. Objetivou-se com este trabalho avaliar retrospectivamente se há diferença nos valores entre pressão arterial média auricular e femoral, com o intuito de indicar qual melhor alternativa para monitoração arterial em pacientes submetidos a hemilaminectomia. Concluiu-se que existe diferença estatisticamente significativa entre valores de pressão arterial femoral e auricular.
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