Context:Equisetum giganteum L. (Equisetaceae) is an endemic plant of Central and South America used in traditional medicine. Natural drugs have been frequently used in the treatment of a myriad of diseases, proving to be an alternative to synthetic chemicals, and have been intensively studied in the prevention of sicknesses, including oral diseases.Objective: This study evaluated the in vitro antiadherent activity of E. giganteum extract against Candida albicans biofilms.Materials and methods: Crystal violet and colony-forming units assays were used to quantify the total biofilm biomass and biofilm living cells on a denture base acrylic resin pretreated with hydroethanolic extract of E. giganteum in different concentrations (50, 25, 16, 8, and 4 mg/mL), after 24 h of biofilm development.Results:Equisetum giganteum affected biofilms by reduction of biomass and living cells per area of acrylic specimens. The results revealed reduction of 15–44% of the biofilm mass and reduction of numbers of colony-forming units (CFUs) present in biofilms (79%) compared to the untreated control (CTRL/PBS). At all concentrations, it demonstrated important antiadherent activity on Candida albicans biofilms, the main microbe in denture stomatitis.Discussion and conclusion: The present findings show that E. giganteum antimicrobial effects may qualify the extract as a promising natural alternative for topical treatment or prevention of denture stomatitis. The usage of drugs made of natural products shows advantages in relation to synthetic drugs on the market, such as lower cost, lower toxicity, and in relation to the occurrence of microbial resistance.
This study aimed to compare two beta-tricalcium phosphates with different particle sizes in human maxillary sinuses lifting. The immunolabeling of cells for RUNX2 and VEGF were performed to evaluate the osteoblast precursor cells and the vascular formation after 6 months of bone repair. Ten maxillary sinuses were grafted with autogenous bone graft (Group 1), 10 were grafted with ChronOs® (Group 2), and 10 were grafted with BETA-TCP® (Group 3). After 6 months of bone healing, biopsies were obtained to assess the new bone formed by histomorphometric and immunohistochemical evaluation for RUNX2 and VEGF. The mean bone formation for Group 1 was 51.4 ± 17.4%. Group 2 presented 45.5 ± 9.9%, and Group 3 conferred 35.4 ± 8.0% of new bone formation. The RUNX2 offered low for Groups 1 and 2 with high cellular activity for osteoblast in Group 3. The VEGF immunolabeling was moderate for Groups 1 and 2 and intense for Group 3. In conclusion, it was possible to show that the bone substitutes evaluated in the present study presented suitable outcomes for bone regeneration, being an alternative for the autogenous bone graft in maxillary sinus bone height reconstruction.
This study investigated the effect of fracture strength and fracture mode characteristics related to reduced interocclusal space on computer-aided design/computer-aided manufacturing (CAD/CAM). ZrO 2 fixed partial denture (FPD) frameworks subjected to quasi-static loads. Materials and Methods: First, two dental implants (4 × 10 mm) were positioned simulating a three-unit FPD (second premolar and second molar abutments). The implants were distributed into two groups: control group (n = 10), positioned at the same level; and the test group (n = 10), where the interocclusal space corresponding to the second molar was reduced by 3 mm in relation to the second premolar to simulate a clinical situation. After FPD wax-up (25-mm long; connector height = 5 mm; connector width = 3 mm, proximal and lingual collar reinforcement), casting was made in a Co-Cr alloy to serve as a prototype. Upon scanning, screw-retained CAD/CAM ZrO 2 FPDs were fabricated for each group. Then, FPDs were subjected to quasi-static axial loading until fracture in the mid-occlusal pontic area using a universal testing machine at the crosshead speed of 0.5 mm/min. Next, the samples were analyzed by scanning electronic microscopy (SEM) to describe the fracture characteristics. Results: The mean fracture strength values for the control group (1,747.4 ± 122.3 N) and test group (1,817.7 ± 158.9 N) showed no significant difference (Student t test, P < .124). The SEM images of the fracture sites revealed two cleavage areas in the test group, providing representative sites with increased fracture energy storage in this group compared with the control group. Conclusion: Within the limitations of this study, the results showed that reduced interocclusal space and reduced length did not decrease the fracture strength of the ZrO 2 FPD frameworks.
Introduction: Esthetics dental treatments involving ceramic laminate veneers can obtain optimal results through detailed considerations with respect to teeth preparations, gingival margins and esthetic factors. Objectives: This case report aims to present a conservative management for ceramic conservative preparation associated with the digital workflow for ceramic laminates, with 18-month follow-up. Case Report: Patient complaining of a child smile due to diastemas in the anterior region. The planning and design of the smile was carried out using a software (Keynote, Ceramill Mind). After molding and printing a 3D model, a mock-up was performed, which was used as a surgical guide for the performance of gingivoplasty. The conservative dental preparation was then performed, with cervical enamel preservation. The ceramic laminates were made after molding and scanning the model, using the CAD/CAM system and cemented on the dental surface. It was observed that there was an increase in gingival quality and thickness, achieving esthetics, color and marginal stability, after 18 months of follow-up. Conclusion: The conservative preparation technique associated with the digital workflow allowed the manufacture of thin ceramic laminate veneer, promoting stability of esthetics and periodontal health after 18 months.
Introdução: São diversos os fatores que podem ocasionar problemas que afetam a estética oral e, entre eles, a ausência de harmonia entre a forma, o alinhamento e a disposição dos dentes anteriores se apresenta como um dos mais frequentemente observados, intensificado pelo escurecimento dental. Objetivo: Analisar se a aplicação de resina composta realizada em um paciente com desgaste dentário pode ser feita através de técnicas minimamente invasivas. Conclusão: As facetas diretas em resina composta representam uma excelente opção, uma vez que os compósitos resinosos nanotecnológicos são capazes de mimetizar de forma natural, confiável e segura a estrutura dentária, através de uma técnica minimamente invasiva, permanecendo satisfatórias por um longo tempo e apresentando excelente custo-benefício. E pode ser feita em pacientes com desgaste dentário de maneira minimamente invasiva a depender do caso de individualidade de cada paciente.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.