The first molecular adducts of platinum and arsenic based anticancer drugs - arsenoplatins - show unanticipated structure, substitution chemistry, and cellular cytotoxicity. The PtII-AsIII bonds in these complexes are stable in aqueous solution and strongly influence the lability of the trans ligand.
Anticancer drugs based on molecular adducts of platinum and arsenic (arsenoplatins) show an unanticipated structure, substitution chemistry, and cellular cytotoxicity. The PtII–AsIII bonds in these complexes are stable in aqueous solution and strongly influence the lability of the trans ligand.
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