Xanthene dyes T 1000 Rhodamine Derivative Bearing Histidine Binding Site as a Fluorescent Chemosensor for Hg 2+ . -The chemosensor (I) displays a highly selective "off-on" type fluorescent change with Hg 2+ . -(KWON, S. K.; KIM, H. N.; RHO, J. H.; SWAMY, K. M. K.; SHANTHAKUMAR, S. M.; YOON*, J.; Bull. Korean Chem.
The need for developing a simple and effective assessment tool for muscle mass has been increasing in a rapidly aging society. This study aimed to evaluate the feasibility of the surface electromyography (sEMG) parameters for estimating muscle mass. Overall, 212 healthy volunteers participated in this study. Maximal voluntary contraction (MVC) strength and root mean square (RMS) values of motor unit potentials from surface electrodes on each muscle (biceps brachii, triceps brachii, biceps femoris, rectus femoris) during isometric exercises of elbow flexion (EF), elbow extension (EE), knee flexion (KF), knee extension (KE) were acquired. New variables (MeanRMS, MaxRMS, and RatioRMS) were calculated from RMS values according to each exercise. Bioimpedance analysis (BIA) was performed to determine the segmental lean mass (SLM), segmental fat mass (SFM), and appendicular skeletal muscle mass (ASM). Muscle thicknesses were measured using ultrasonography (US). sEMG parameters showed positive correlations with MVC strength, SLM, ASM, and muscle thickness measured by US, but showed negative correlations with SFM. An equation was developed for ASM: ASM = −26.04 + 20.345 × Height + 0.178 × weight − 2.065 × (1, if female; 0, if male) + 0.327 × RatioRMS(KF) + 0.965 × MeanRMS(EE) (SEE = 1.167, adjusted R2 = 0.934). sEMG parameters in controlled conditions may represent overall muscle strength and muscle mass in healthy individuals.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.Elevated immunoglobulin E (IgE) can be detected in various conditions such as allergic asthma, atopic eczema, anaphylaxis, parasite infection, vasculitis, IgE myeloma, and hyper-IgE syndrome (HIES).1 The binding of IgE to specific antigens causes mast-cell degranulation, resulting in an inflammatory reaction. 2 Here we present a patient with Guillain-Barré syndrome (GBS) who exhibited elevated serum IgE.
CASEA 72-year-old man was admitted for paresthesia in both feet and a gait disturbance that had progressed for the previous 3 days. He was generally healthy except for frequent skin abscesses and eczema. Peripheral neuropathy associated with hyper-IgE-emia have been rarely reported. Here we present a 72-year-old man with acute motor axonal neuropathy who had relatively poor prognosis. The serum was weakly positive for IgG GQ1b and GT1a, and serum IgE was significantly elevated. He was transferred to a rehabilitation center with Medical Research Council grade 3 lower extremity weakness on admission day 65. We would suggest that hyper-IgE-emia may increase the magnitude and rate of neural damage in this case.
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