The magnitude of the possible improvement in HbA1c agrees well with other studies in the relation between adherence and HbA1c levels. The estimated numbers suggest that missing injections are an important reason for suboptimal treatment.
We showed how blood glucose prediction is severely affected by the inaccuracy in the input variables. Metabolic fluctuations, causing variability in insulin dynamics, also display important effects, but these are difficult to change. The inaccuracy of carbohydrate counting and the use of blood glucose meters appear to be the two main sources of error, which can be reduced through better patient education.
The DIAdvisor is an EC/FP7 funded project aiming at the development of a Blood Glucose prediction device which uses easily available information to optimise the therapy of patients with diabetes.
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