In an unselected cohort of patients admitted with AMI, the mortality was considerably higher than expected from voluntary-based registries and large-scale clinical trials. The most favourable outcome is observed in patients with STEMI.
His or para-His pacing preserves LVEF and mechanical synchrony as compared with RVSP after 12 months pacing in patients with AVB, narrow QRS, and LVEF > 0.40.
In a cohort of patients scheduled for admission to a local hospital and subsequent transferral to an interventional centre for primary PCI, those diagnosed pre-hospitally had shorter treatment delay compared with those diagnosed in hospital, both in the setting of initial admission to a local hospital, and to an even larger extent in the setting of referral directly to the interventional centre.
STEMI patients transferred for primary PCI are heterogeneous with respect to pre- and per-interventional ST-changes, and a pre-specified ST-monitoring classification seems useful for stratification of patients at time of PCI into groups with low, intermediate, and high risk profile. Furthermore, post-interventional ST-monitoring indicates that traditional 90 min ST-resolution analysis may have limited value in the era of primary PCI.
Ablative therapy of AT in ToF patients is an effective curative treatment modality with a high procedural success rate. Sinus rhythm during long-term follow-up was obtained in the majority of patients. Fifty-one of 52 AT originated from sites related to surgical incisions created at complete repair, suggesting that extending the atriotomy incision towards the inferior caval vein during cardiac surgery combined with surgical ablation of the cavo-tricuspid isthmus will be effective in preventing development of AT.
Cardiac implantable electronic device (CIED) infection, according to current trends, appears to be an increasing problem. It can be indolent and its diagnosis challenging. Cardiac implantable electronic device infections are potentially lethal, and timely diagnosis and early initiation of correct treatment are of highest importance for patient prognosis. For reducing CIED infections, careful patient selection, preventative measures, and appropriate choice of device are key. The current review presents available data and consensus opinion within the field of CIED infection and identifies important current practice points and aspects for future development. Strategies for reducing CIED infection should be tested in sufficiently powered and well-designed multicentre randomized controlled trials.
Stable direct His-bundle pacing or para-His pacing is feasible in 85% of patients with narrow QRS and high-grade AV block and leads to a normal or near-normal ventricular activation pattern.
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