A series of chiral iridacycles have been synthesised and shown to be moderately enantioselective in asymmetric transfer hydrogenation reactions.

Oil-in-water emulsions are centrifuged to generate a gradient distribution of emulsion droplets. This structure is locked by freezing or polymerization and the subsequent removal of the solvents produces gradient porous materials.

[reaction: see text] Benzo[b]furan-3-carboxylic acid (2) was generated from 1 by forming three new bonds in one step via a Pd(II)-mediated cascade carboxylative annulation. The proposed mechanism was supported by the observation of an unusual acetylation of 1 as a side reaction together with an (18)O-labeling study.

This report was prepared as an account of work sponsored by an agency of the United States Government.

No abstract

2005 Benzofuran derivatives R 0070 Novel Pd II -Mediated Cascade Carboxylative Annulation to Construct Benzo[b]furan-3-carboxylic Acids. -A novel and mild method for the rapid synthesis of benzo[b]furan-3-carboxylic acids directly from the substituted o-alkynyl-phenols in good yields by utilizing a Pd(II)-mediated carboxylative annulation is developed. Three new bonds are formed in one step. -(LIAO*, Y.; SMITH, J.; FATHI, R.; YANG, Z.; Org. Lett. 7 (2005) 13, 2707-2709; VivoQuest., Inc., New York, NY 10989, USA; Eng.) -Y. Steudel 44-121