EVLA using the tulip catheter avoids ulceration and perforation of the vein associated with treatment using a bare fibre. It also results in more even circumferential vein wall necrosis and less perivenous tissue destruction.
The ELT of veins produces an unevenly distributed damage. The cell necrosis is far more extensive than expected. Uneven vein wall destruction can lead to recanalization. Using a 1500 nm laser correlates with less penetrating ulcerations and more circumferential damage.
A higher intraluminal blood volume results in reduced total vein wall destruction. Injection of tumescent liquid prevents the perivenous tissue destruction and minimises the number of perforations.
The Y-chromosome is a widely studied and useful small part of the genome providing different applications for interdisciplinary research. In many (Western) societies, the Y-chromosome and surnames are paternally coinherited, suggesting a corresponding Y-haplotype for every namesake. While it has already been observed that this correlation may be disrupted by a false-paternity event, adoption, anonymous sperm donor or the cofounding of surnames, extensive information on the strength of the surname match frequency (SMF) with the Ychromosome remains rather unknown. For the first time in Belgium and the Netherlands, we were able to study this correlation using 2,401 males genotyped for 46 Y-STRs and 183 Y-SNPs. The SMF was observed to be dependent on the number of Y-STRs analyzed, their mutation rates and the number of Y-STR differences allowed for a kinship. For a perfect match, the Yfiler® Plus and our in-house YForGen kit gave a similar high SMF of 98%, but for non-perfect matches, the latter could overall be identified as the best kit. The SMF generally increased due to less mismatches when encountering [1] deep Y-subhaplogroups, [2] less frequently occurring surnames, and [3] small geographical distances between relatives. This novel information enabled the design of a surname prediction model based on genetic and geographical distances of a kinship. The prediction model has an area under the curve (AUC) of 0.9 and is therefore useable for DNA kinship priority listing in estimation applications like forensic familial searching.
Policies, measures, and models geared towards flood prevention and managing surface waters benefit from high quality data on the presence and characteristics of drainage ditches. As a cost and labour effective alternative for acquiring such data through field surveys, we propose a method (a) to extract vector data representing ditch drainage networks based on local morphologic features derived from high resolution digital elevation models (DEM) and (b) to identify possible connections in the ditch network by calculating a probability of the connectivity using a logistic regression where the predictor variables are characteristics of the ditch centre lines or derived from the DEM. Using Light Detection and Ranging (LiDAR) derived DEMs with a 1 m resolution, the method was developed and tested for a mixed agricultural residential area in north-eastern Belgium. The derived ditch segments had an error of omission of 8% and an error of commission of 5%. The original positional accuracy of the centre lines of the extracted ditches was 0.6 m and could be improved to 0.4 m by shifting each vertex to the position of the lowest LiDAR point located within a radius equal to the spatial resolution of the used DEM. About 69% of the false disconnections in the network were identified and corrected leading to a reduction of the unconnected parts of the ditch network by 71%. The extracted and connected network approximated the reference ditch network fairly well.
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