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67coagulation at which the risk becomes clinically relevant are totally unknown. The results of this study, despite these limitations, may help to rationalise anaesthetic practice with regard to requests for coagulation screens on such patients.
AcknowledgmentsWe thank Professor A.L. Bloom
SummaryPain on injection of propofol was assessed in a controlled, randomised study of 273 patients. They received either lignocaine 10 mg, procaine 10 rng or isotonic saline 0.5 ml, 15 seconds before the injection of propofol into a vein on the back of the hand. The incidence of pain on injection in the'control group (51 %) was comparable with other studies. Lignocaine and procaine both significantly reduced the pain (35% and 34% respectively, p < 0.05) but there was no statistical difference between these two groups.
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