We have introduced the error curve method, an analysis technique which allows the quantitative determination of gamma criteria sensitivity to induced errors. The application of the error curve method using DMLC IMRT plans measured on the ArcCHECK® device demonstrated that large errors can potentially be missed in IMRT QA with commonly used gamma criteria (e.g., 3%/3 mm, threshold = 10%, 90% pixels passing). Additionally, increasing the dose threshold value can offer dramatic increases in error sensitivity. This approach may allow the selection of more meaningful gamma criteria for IMRT QA and is straightforward to apply to other combinations of devices and treatment techniques.
A hybrid VMAT∕IMRT strategy was implemented to find a high quality compromise between gantry-angle and intensity-based degrees of freedom. This optimization method will allow patients to be simultaneously planned for dosimetric quality and delivery efficiency without switching between delivery techniques. Example phantom and clinical cases suggest that the conversion of only three VMAT segments to modulated beams may result in a good combination of quality and efficiency.
Purpose To separately quantify sensitivity differences in patient‐specific quality assurance comparisons analyzed with the gamma comparison for different measurement geometries, spatial samplings, and delivery techniques [intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT)]. Methods Error‐free calculations for 20 IMRT and 20 VMAT cases were compared to calculations with known induced errors of varying magnitudes, using gamma comparisons. Five error types (MU scaling, three different MLC errors, and collimator errors) were induced in plan calculations on three different detector geometries – ArcCHECK, MapCHECK, and Delta 4. To study detector geometry sensitivity effects alone, gamma comparisons were made with 1 mm error‐free calculations compared to 1 mm error‐induced calculations for each device. Effects of spatial sampling were studied by making the same gamma comparisons, but down‐sampling the error‐induced calculations to the real spatial sampling of each device. Additionally, 1 mm vs 1 mm comparisons between the IMRT and VMAT cases were compared to investigate sensitivity differences between IMRT and VMAT using IMRT and VMAT cohorts with similar ranges of plan complexity and average aperture size. For each case, induced error type, and device, five different gamma criteria were studied to ensure sensitivity differences between devices, spatial sampling scenarios, and delivery technique were not gamma criterion specific, resulting in over 36,000 gamma comparisons. Results For IMRT cases, Delta4 and MapCHECK devices had similar error sensitivities for lagging leaf, bank shift, and MU errors, while the ArcCHECK had considerably lower sensitivity than the planar‐type devices. For collimator errors and perturbational leaf errors the ArcCHECK had higher error sensitivity than planar‐type devices. This behavior was independent of gamma parameters (percent dose difference, distance‐to‐agreement, and low dose threshold), though use of local normalization resulted in error sensitivites that were markedly similar between all three devices. Differences between detector geometries were less pronounced for VMAT deliveries. Error sensitivity for a given gamma criterion when comparing IMRT and VMAT deliveries on the same devices showed that VMAT plans were more sensitive to some specific error types and less sensitive to others, when compared to IMRT plans. For the ArcCHECK device, the sensitivity of IMRT and VMAT cases was quite similar, whereas this was not the case for the planar‐type devices. When comparing error sensitivity between 1 mm vs 1 mm calculations and 1 mm vs the real spatial sampling for each device, results showed that increased spatial sampling did not systematically increase error sensitivity. Conclusions Noticeable differences in error sensitivity were observed for different detector geometries, but differences were dependent on induced error type, and a particular device geometry did not offer universal improvements in error sensitivity across studied error types. Thi...
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