Objective: To compare the efficacy of solifenacin and oxybutynin in the treatment of overactive bladder in female patients. Study Design: Quasi Experimental study. Setting: Department of Urology, Institute of Kidney Diseases, Peshawar. Period: July 2018 to May 2019. Material & Methods: After selection of 312 female patients with overactive bladder by simple random sampling, written informed consent was taken and pre-treatment overactive bladder symptoms (OABS) score was calculated. Patients were randomly distributed in two equal groups of 156 subjects, where Group A received Oxybutynin (3 mg, BD) and Group B received Solifenacin (5mg, OD) for a period 12 weeks. Patients were called for follow up visit to determine and compare the efficacy of study drugs. Those who showed improvement in at least 03 points in OABS score taken pre-treatment were considered as positive responders. Results: The mean age of patients was 38.8 ± 7.62 years with age range from 20 to 50 years. 110 (70.5%) subjects in oxybutynin treated group while 126 (80.8%) subjects in solifenacin treated group reported significant improvement in OAB symptoms. Conclusion: Solifenacin is relatively more effective than oxybutynin for treating female patients with overactive bladder.
Background and Aim: The renal stones of any size could be effectively managed through an essential surgical technique known as Percutaneous Nephrolithotomy (PCNL). The large size renal stones with abnormal kidneys imposed additional challenges for PNCL in anomalous kidneys. The present study aimed to evaluate the effectiveness and safety of Percutaneous Nephrolithotomy in malrotated kidneys. Place and Duration: Conducted at Urology department of Mian Gul Abdulhaq Jehanzeb Kidney Hospital Manglawar, Swat for duration of two years (from May 2019 to April 2021). Materials and Methods. This single-centered retrospective study was conducted on 80 patients who underwent percutaneous nephrolithotomy with malrotation kidneys. The individuals with anomalous kidneys and complex calculi were enrolled in this study. These patients had kidneys anomalies such as horseshoe kidneys, crossed fused ectopia, malrotation kidneys, pelvic and complete stone clearance. Posterior or anterior approaches were followed for the procedure after preoperative evaluation in kidney anomalies. Retrograde catheterization was carried out under spinal and general anesthesia with the patients. For all the patients, stone size and clearance were measured. Results: Of the total 80 kidneys anomalies patients, 55 (68.7%) were male and 25 (31.3%) were females. Overall mean age was 35.26 ± 13.51. The stone size varied from 1.3cm to 7 cm. Patients were categorized into two groups based on stone sizes such as group I (1.3-2.5 cm) had 42 (52.5%) and group II (25-7cm) 38 (47.5%) patients. The patients included renal pelvis 19 (23.6%), the pelvic ureteric junction (PUJ) 8 (10%), horseshoe kidneys 2 (2.5%), crossed fused ectopia 9 (11.3%), and malrotation kidneys 3 (3.8%).The stone clearance was completed in 77 (96.3%) patients. The statistically significant factor for complete clearance was the staghorn stone calculus. Conclusion: Percutaneous nephrolithotomy is a safe and effective procedure for large renal stones management in patients of anomalous kidneys. Higher renal stones clearance can be achieved with minimum morbidity by suitable preoperative evaluation and technical experts. Keywords: Malrotated kidney; Nephrostomy, Percutaneous; Nephrolithiasis; Abnormality
The study was carried out with the core objective about Islamic principles and teachings regarding welfare and its observance in ‘Pakhtun’ society under interpretative methodology of social sciences in ‘Gadhar-Hamza Khan, Shankar and Jamal Garhi’ of District Mardan. For collection of the relevant primary data 30 participants were purposely selected through convenient sampling method and then thoroughly interviewed while using interview guide as tool of data collection. After collection of the data, different themes were derived which were properly analyzed and presented in sequential orders. The study concluded that the most of the participant were lacking enough knowledge about calculation and distribution Zkwāt and ‘Ashr as they used and considered both term terms interchangeably. The study further concluded that priority was given to ‘Ashr rather Zkwāt. Awareness and observance about teachings of Islam in true spirit, inclusion of reading materials in curriculum of schools, colleges and universities, and deliverance of religious sermons by clerics about promotion of welfare activities were presented some of the recommendations.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.