No abstract

Articles you may be interested inEffect of rolling motion on local characteristics of gas-liquid two-phase flow using an optical probe AIP Conf.

This paper presents promising microfluidic devices designed for continuous and passive extraction of plasma from whole human blood. These designs are based on red cells lateral migration and the resulting cell-free layer locally expanded by geometric singularities such as an enlargement of the channel or a cavity adjacent to the channel. After an explanation of flow patterns, different tests are described that confirm the advantages of both proposed singularities, providing a 1.5 and 2X increase in extraction yield compared to a reference device, for 1:20 diluted blood at 100 microL/min. Devices have also been successively optimized, with extraction yields up to 17.8%, and biologically validated for plasma extraction, with no protein loss or denaturation, no hemolysis and with excellent cell purity. Finally, the dilution effect has been experimentally investigated.

The numerical simulation using a boundary element method is presented for a gas bubble bursting at a free surface in a potential flow with a viscous fluid assumption. Systematic comparisons are given with experimental data on the first "jet drop" size in relation with the parent bubble size, and on the critical bubble radius above which no jet drop forms. The computations were made for different liquids. It is pointed out that an exact description of the jet formation and break up requires the complete Navier-Stokes equations only in the final phase of the evolution.

No abstract