The identification of ultrastructural patterns in these nephropathies is important. GN with organized microtubular monoclonal deposits (GOMMID) probably accounts for a large proportion of immunotactoid (microtubular) GN cases.

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The report of a clinical study of 104 electrical accidents which befell 85 men is divided into two parts.Part I enumerates the different types of accidents as flash burn, Joule burn, arc eye, "held on" shock and "not held" shock, physical shock, and death. These are related to the different voltages involved ranging from 240/415 (medium) voltage to 33 kilovolts. There appeared to be no association between voltage and type of injury and no evidence to suggest that any of the voltages are free from hazard. There were 53 cases of flash burn, affecting mostly the face and extensor surface of the hands and arms. The 16 cases of arc eye caused no serious concern. Of the 15 Joule burns all except one occurred at medium voltages in "held on" accidents, the other being associated with an electric shock at 33 kilovolts. The majority of Joule burns affected the flexor surfaces.Part II of the paper deals with the 43 cases of electric shock (passage of current through the body). Thirty of these cases were "held on" to the circuit by the current. It was found that the longer a victim was held on to the circuit the greater appeared to be his chances of developing heart and chest symptoms suggestive of impending asphyxia, and of losing consciousness. Although about half of these men were released by an external agmncy and others struggled off, a number suddenly became free from the circuit without, they claimed, losing consciousness. This is difficult to explain. Artificial respiration was administered in two cases, one of whom was "held on" and was being asphyxiated. The other case received flash burns only and did not in fact receive an electric shock. PART I: GENERAL REVIEW AND NON-SHOCK CASESElectrical accidents receive little attention in British medical literature. In fact, in the electricity supply industry they account for only 1 % of the total number of accidents but they are the commonest cause of accidental death (Hughes and Corney, 1956). In factories, electrical accidents account for less than 0-5 % of all accidents, but more than 5% of these electrical accidents prove fatal (Emerson, 1961). This paper reports a clinical investigation into a series of electrical accidents; detailed consideration of the cases of electric shock (passage of current through the body) is given in Part II of this paper. MethodThe names of all men in an electricity supply undertaking who had sustained an electrical accident during the preceding three years were obtained. Of the total of 114, 107 were still employed by the undertaking. One man was killed; the remainder were contacted and 84 attended for interview. (The majority of those who were not seen worked in one small area and there is no reason to suppose that the nature of their accidents was any different from the whole.) They were all seen by one investigator and were questioned about the electrical and physical circumstances of the accident, about symptoms, and about subsequent medical history.

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Burkitt's-type lymphomas-leukaemias (BL) are monoclonal proliferations of malignant B lymphocytes. Irrespective of whether they carry the Epstein-Barr virus (EBV) genome, these tumour cells have been shown consistently to have one of the specific reciprocal chromosome translocations, t(8; 14), t(2; 8) or t(8; 22), involving the long arm of chromosome 8 (on 8q24) and chromosome 14, 2 or 22 (on 14q32, 2p12 and 22q11, respectively). The latter chromosomes have been shown recently to carry genes for immunoglobulin (Ig) heavy chains, and kappa and lambda light chains, respectively. Furthermore, the localization of kappa light chains within 2pcen-2p13 encompasses the breakpoint observed in Burkitt's translocation (2p12). It was therefore considered of interest to determine whether the expression of immunoglobulin chains in BL cells is related to the type of chromosomal anomalies observed. We report here that there is a direct relationship between expression of immunoglobulin light chains and specific type of translocation: BL cells with t(8; 22) express lambda chains, whereas those with t(2; 8) express kappa chains.

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