Purpose: To identify changes in vascular morphology on magnetic resonance imaging (MRI) in patients with cirrhosis and to compare these findings to liver donors. Materials and Methods:Patients undergoing liver transplantation with biopsy-proven cirrhosis (n ϭ 74) and liver donor candidates (n ϭ 85) underwent dynamic gadoliniumenhanced 3D MR at 1.5T. Vessel diameters were measured independently by three radiologists and features of cirrhosis were identified and correlated with cirrhosis.Results: Hepatic veins were smaller in patients with cirrhosis (4.9, 4.5, and 5.0 mm for right, middle, and left vs. 9.9, 7.6, and 8.9 mm in donors, P Ӷ 0.001) and were negatively correlated with cirrhosis (P Ͻ 0.001). Right hepatic vein (RHV) Ͻ5 mm diagnosed cirrhosis with 59% sensitivity and 99% specificity; the sensitivity and specificity were 88% and 85% for RHV Ͻ7 mm. Main portal vein was minimally larger in cirrhosis, 14 versus 12 mm (P Ͻ 0.001) in donors. Right portal veins were smaller in cirrhotic patients, 6.5 and 6.2 mm compared to 8.4 and 7.6 mm (P Ӷ 0.001), respectively, in donors. Conclusion:Vascular features of cirrhosis include small hepatic veins, minimally enlarged main portal vein, and small intrahepatic portal veins; these features may facilitate identification of cirrhosis.
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