Staphylococcus aureus is a gram positive coccus responsible for severe morbidity and mortality as it causes community and hospital acquired infections. The Methicillin resistant Staphylococcus aureus is responsible for several difficult to treat infections in human. Objectives: To find out Frequency of Methicillin resistant Staphylococcus aureus in Patients in a tertiary care hospital of Lahore. Study Design: Cross-sectional study. Setting: Tertiary care (Services Hospital) Lahore. Period: Four months from 1st August 2017 to 30th November 2017. Material & Methods: A total of 2534 isolates were obtained during the period (1 August 2017 to 30 November 2017) from patients at a tertiary care hospital of Lahore. Specimen were inoculated on blood agar plates, strains obtained were confirmed for Staphylococcus aureus using conventional biochemical tests and oxacillin disk test was performed to confirm methicillin resistant Staphylococcus aureus. Result: Out of 104 Staphylococcus aureus isolates, methicillin resistant Staphylococcus aureus was 46 (44.2%) and methicillin sensitive Staphylococcus aureus was 58 (55.8%). Conclusion: Methicillin resistant Staphylococcus aureus is a big challenge for current health care system and this may be a cause of morbidity and mortality in community and hospital patients.
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