Amoebic liver abscess (ALA) is the commonest extra-intestinal manifestation of amoebic infection. Unfortunately, there is confusion among medical community regarding management of amoebic liver abscess. Aims: To assess outcome of patients with uncomplicated ALA treated using conservative approach. Methodology: Prospective, observational study was carried out over period of 2 year. Amoebic liver abscess was diagnosed on clinical, ultra sonographic, and serological features. All patients were treated with metronidazole. The indication for ultrasound guided aspiration of abscess was failure to improve clinically within 48 -72 hours Complications and outcome of patients were noted. Results: 80 (80%) patients were managed conservatively and 20 (20%) patients were managed by aspiration. 32% in 31-40 years of age group. 93% were male. We found the study participants who required intervention as a line of management had more deranged liver functions and that to found statistically significant. Conclusion:Conservative medical management of amoebic liver abscess is safe and effective.
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