This study shows that cow's milk can cause wheezing in children with asthma. Although SPT seemed to be more reliable than sIgE testing, both had suboptimal reliability. It is worth considering possible milk allergy in children with asthma, particularly when poorly controlled in spite of proper routine management.
Immunoglobulin E (IgE)-mediated allergic diseases are common in India. The majority of the patients suffer from bronchial asthma, allergic rhinitis or both. The diagnosis of these conditions is based on clinical history and examination, however establishment of allergy requires either skin prick testing (SPT) or measurement of serum-specific IgE (SSIgE) levels to relevant allergens. The diagnostic modalities measuring in vitro SSIgE levels include radioallergosorbent test (RAST) and ImmunoCAP methods. [1][2][3][4] Results from western literature have shown SPT to be more sensitive than SSIgE. 2-4 Hence, SPT is more commonly used in allergy testing, while in vitro tests are considered to be complementary. 3 Skin prick testing has been considered to be the 'gold standard' in the assessment of inhalant allergen sensitivity. Results are interpreted in the context of clinical history and epidemiological profile. Allergy is diagnosed
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