To determine raised serum hsCRP levels, an established risk marker in stroke patients and also to study the co relation between raised serum uric acid and hsCRP levels in ischemic and hemorrhagic stroke. MATERIALS AND METHODS: This was a cross sectional study of 200 patients presenting with a history of focal neurological deficit of acute onset in the form of hemiparesis, hemiplegia having evidence of presence of ischemic or hemorrhagic infarct in CT scan of brain. In all patients hsCRP levels were measured within 48hours of presentation. RESULTS: Most of the patients (65%) were in the age group of more than 50 years. Left-sided hemiparesis with altered sensorium and UMN facial palsy was the most common presenting symptom. hsCRP levels were found to be increased in hemorrhagic stroke patients than with ischemic stroke, this difference was found to be statistically significant (p < 0.001). CONCLUSION: From this study we concluded that hsCRP level is increased in cases of stroke-ischemic as well as hemorrhagic, but more in hemorrhagic stroke suggesting an inflammatory response in acute stroke. Furthermore, the increased levels correlated with larger bleed and infarct size, severe neurological deficit and worse outcome.

Strong association has been found between high levels of serum cholesterol, especially of low-density lipoprotein (LDL) cholesterol and the development of atherosclerosis, while elevated levels of high-density lipoprotein (HDL) cholesterol seem to play a protective role. However, evidence linking blood lipids to cerebrovascular diseases has failed to put an end to a long-standing controversy. Studies have shown that the advent of HMCoA reductase inhibitors (Statins), has contributed new evidence supporting association of total cholesterol and LDL levels with risk of Cerebral Ischemia has decreased with no change in risk for hemorrhagic stroke. Objective of this study was to identify different components of lipids in relation to type of stroke, i.e., cerebral ischemia or cerebral haemorrhage. METHODSAn observational study was conducted to determine differences in serum lipid levels among individuals suffering different types of stroke. Participants included patients in the acute phase of stroke admitted to Victoria Hospital, Bangalore Medical College and Research Institute (BMCRI). Lipid profile was estimated in these patients. RESULTSTotal of 276 patients with documented stroke were included in the study. Of the 227 total patients, 71.73% (198) were male patients. Lipid components was found to be higher in ischemic stroke compared to hemorrhagic stroke. STATISTICAL METHODSDescriptive and inferential statistical analysis has been carried out in the present study. CONCLUSIONSHigh levels of total cholesterol, LDL, and triglycerides were associated with occurrence of atheromatous cerebral infarction, while low levels of total cholesterol and high levels of triglycerides are linked with occurrence of cerebral hemorrhage.