For various reasons, the cloud computing paradigm is unable to meet certain requirements (e.g. low latency and jitter, context awareness, mobility support) that are crucial for several applications (e.g. vehicular networks, augmented reality). To fulfil these requirements, various paradigms, such as fog computing, mobile edge computing, and mobile cloud computing, have emerged in recent years. While these edge paradigms share several features, most of the existing research is compartmentalised; no synergies have been explored. This is especially true in the field of security, where most analyses focus only on one edge paradigm, while ignoring the others. The main goal of this study is to holistically analyse the security threats, challenges, and mechanisms inherent in all edge paradigms, while highlighting potential synergies and venues of collaboration. In our results, we will show that all edge paradigms should consider the advances in other paradigms.

In this retrospective study, we analyzed the outcomes of 129 patients who underwent an allogeneic hematopoietic stem cell transplantation (allo-HSCT) and had a history of probable or proven invasive aspergillosis (IA), of whom 57 (44%) received a reduced-intensity conditioning (RIC). Overall, 27 patients with IA progressed after the allo-HSCT (cumulative incidence [CumInc] at 2 years, 22%). The variables that increased the 2-year CumInc of IA progression were (1) longer duration of neutropenia after transplantation; (2) advanced status of the underlying disease; and (3) less than 6 weeks from start of systemic anti-Aspergillus therapy and the allo-HSCT. In addition, (4) conventional myeloablative conditioning increased the risk of progression early after transplantation (before day 30) only, while 3 variables increased the risk beyond day 30 were (5) cytomegalovirus disease; (6) bone marrow or cord blood as source of stem cells; and (7) grades II to IV acute graft-versus-host disease (GVHD). A risk model for progression was generated, defined as low (0-1 risk factors, 6% incidence), intermediate (