The purpose of this research is to reveal the possible relational influence of age on frequency and form of music consumption, its use, and value as a factor associated with emotional self-regulation in pandemic contexts. With this objective, this study applied a transversal, descriptive and analytical design in a sample of 1377 Spaniards during the confinement of COVID-19 from March 14 to June 20, 2020. The results report that music has been an essential generalized support for living with isolation and a powerful instrument for emotional self-regulation and relief from loneliness. Although an increase of 56% in the daily use of music for self-regulation of emotions was detected, higher frequencies of consumption, mainly in solitude, and a better conception of this artistic expression are identified in the population over 51 years old. However, young people between 18 and 40 years old stood out in the use of music as a resource to alleviate loneliness. These results confirm that music seems to have arisen as one of the most used artistic expressions to cope with loneliness, to relate to the outside or as a tool to endure psychological and emotional states catalogued as negative such as anxiety, anguish and depression, among others. Likewise, they evidence its role in personal and social wellbeing in distant age ranges, and the relational influence of music and age in contexts of isolation and loneliness.