We hypothesized that combination of cisplatin and LBH589 can override cisplatin-associated resistance in ovarian cancer cells. These results provide initial evidence for testing this combination in clinical use.
Consider a composite sandwich plate with balanced or unbalanced anisotropic composite laminated faces and an ideally orthotropic core. A closed-form solution of the buckling load is derived for the composite sandwich plates consisting of cross-ply symmetric laminate faces with all edges simply supported. In addition, a general scheme is developed for the composite sandwich plates with arbitrary sandwich layups, boundary, and loading conditions. By combining the present buckling analysis with PowelPs conjugate direction method, an optimal algorithm is established to find the optimal sandwich layup in resisting biaxial compression, as well as in-plane shear loads.
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