In optic pathway glioma (OPG), bevacizumab-based therapy (BBT) has
promising effects on radiographic tumor burden, but impact on vision is
less clear. This single-institution study characterized visual acuity
(VA) and visual field (VF) outcomes in 17 pediatric OPG patients treated
with BBT. VA was stable or improved in 14 patients. Nine patients had
evaluable VF data, 6 of whom experienced stability or improvement. Among
6 patients with vision deterioration as a treatment indication, stable
or improved was observed for both VA and VF in 5 patients. In summary,
BBT was associated with favorable visual outcomes in most patients with
OPG.
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