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Surgeons carefully assess the risks and benefits of treatment before consenting to perform operative interventions. They are influenced by objective findings and by affective factors such as courage and the determination to survive expressed by their patients. They manage risks, doubts, and fears-both their patients' and their own-relying on trust and commitment on both sides to ensure the success of the surgical mission. The trust of their patients has a strong influence on the surgeons' decisions and actions.

Nelson Goodman's distinction between autographic and allographic arts is appealing, we suggest, because it promises to resolve several prima facie puzzles. We consider and rebut a recent argument that alleges that digital images explode the autographic/allographic distinction. Regardless, there is another familiar problem with the distinction, especially as Goodman formulates it: it seems to entirely ignore an important sense in which all artworks are historical. We note in reply that some artworks can be considered both as historical products and as formal structures. Talk about such works is ambiguous between the two conceptions. This allows us to recover Goodman's distinction: art forms that are ambiguous in this way are allographic. With that formulation settled, we argue that digital images are allographic. We conclude by considering the objection that digital photographs, unlike other digital images, would count as autographic by our criterion; we reply that this points to the vexed nature of photography rather than any problem with the distinction.

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HighlightsTo our knowledge, this is the first study to report resting state functional connectivity (FC) abnormalities associated with focal epilepsy caused by a single cerebral cavernous malformation (CCM).We show, by comparing to the data acquired from the age and gender matched control group, that this type of focal epilepsy is associated with the disruption of the normal regional and global FC. The disruption includes a decrease in the coactivation between the region surrounding the CCM lesion, i.e., the lesional region, and its homotopic counterpart, a reduction in FC between the lesional region and the rest of the brain, and decreased FC among the default mode network (DMN).These changes may be alleviated or reversed after the surgical resection of the CCM and the epileptogenic zone has successfully stopped recurrent seizures.Finally, the severity of the FC disruption in the brain tissue adjacent to the CCM may be used to delineate the epileptogenic zone and to aid the surgical resection.

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In this paper I distinguish the category of “rationalization” from various forms of epistemic irrationality. I maintain that only if we model rationalizers as pretenders can we make sense of the rationalizer's distinctive relationship to the evidence in her possession. I contrast the cognitive attitude of the rationalizer with that of believers whose relationship to the evidence I describe as “waffling” or “intransigent”. In the final section of the paper, I compare the rationalizer to the Frankfurtian bullshitter.