Periodontitis is a chronic inflammation that effect the tissue that surround and support the teeth, and this is prevalent cause of teeth loss in adults while prostatitis is a comparatively common issue affecting about 12 percent of men, and it’s the most common prostate-related health issue in men under age fifty. Researches showed that the heart diseases spread in the persons that have periodontitis about 25-50{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47} higher than healthy persons. Recent studies have connected periodontal disease with plenty of systemic health risks, including heart disease and prostatitis but their results were varied. The recent study aimed to explore the linking of gum diseases with heart diseases and prostate inflammations. In total, 150 serum samples of four age groups of participants distributed as 100 (66.7{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}) samples of patients with periodontitis and other 50 (33.3{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}) samples of control, All patients were attending to Ibn al-Bitar hospital, teaching laboratories – Medical city and Specialized Dental Center/AL-Alwiya and the diagnosis of all cases based up on patients medical history that evaluated by qualified physicians and some other laboratory investigations. As (38.0{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}) patients with heart diseases history and (58.6{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}) patients with prostatitis. Sample were analyzed for Triglycerides, Prostate-specific antigen (PSA) and CRP levels. The abnormal Triglycerides level estimated by (37.3{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}), while the elevated level of (PSA) was determined by (40.0{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}). Furthermore, the prevalence of CRP seropositivity in individuals increased by (43.3{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}). The incidence of periodontal disease (PD) was paralleled with the positivity of tested biochemical markers of cardiovascular disease (CVD) history and prostatitis respectively with high significant differences (P= 0.000). Finally, there is significant connection of PD with CVD and prostatitis, but further studies are needed, and the outcomes of this study have limitations, also the current finding encourages to review a large sample size with different age groups in order to clarify this issue.
To study the role of potential relationship of chronic human herpes virus types (3 – 6) infection and their correlation with the up-regulation of some cytokines (IL-2, IL-10 and IFN gamma) and effect of (8-OHdG) and (TAOC) levels onto male infertility. A Case – control study with semen samples which were collected by masturbation during the routine semen analysis of a total ninety age-matched participants as; fertile males 35 (38.9%) with proven fertility as a normal semen quality and infertile males 55 (61.1%) with at least one year of infertility and poor semen quality. All semen biomarkers of Human herpes viruses (HHVs): Varicella zoster virus (VZV-IgG), Epstein-Barr virus (EBV-IgG), Cytomegalovirus (CMV-IgG), Human herpes virus type 6 (HHV6-IgG), Interlukin-2 (IL-2), Interlukin-10 (IL-10), Interferon-gamma (IFN-γ), 8-hydroxy-2'-deoxy guanosine (8-OHdG) and Total Antioxidant Capacity (TAOC) which were included in the study had been estimated by quantitative ELISA based method and the correlations with sperms parameters were evaluated. The main significant outcomes in this study of the infertile males group 55 (61.1%) were: high percentages of seminal IgG; N (%; Mean±SD) were detected of HHV6, 48 (53.3%;1.26± 0.51) then CMV, 39 (43.3%;1.51± 0.95) followed by EBV, 34 (37.8%; 2.20±1.47), and the highest abnormal cytokines levels were estimated in; 44 (48.9%; 112.62±38.64) and 40 (44.4%; 22.75±10.65) for IFN-γ and IL-10 respectively. Furthermore, High 8-OHdG level was detected in 47 (52.2%;7.29±2.15) and very low level of TAOC was detected in 16 (17.8%;19.34±12.17). Significant negative correlation between semen biomarkers and standard sperms parameters was found which were represented by: 45 (50.0%) of total sperms count less than (33 million ml), 52 (57.8%) of progressive motile sperms less than (31%). Finally, about 33 (24.4%) of abnormal sperm morphology was detected. Our results hypothesized that chronic asymptomatic viral infection with increasing of cytokines concentrations consequently disturbance the semen oxidative status, antioxidant defense systems that induce sperms DNA damage then might be collectively act as a co-factors on the etiology of the male infertility.
The main purposes of this study were to find out the possible correlation of CMV & EBV infections with high blood pressure initiation in some groups of hypertensive Iraqi patients, also to determine the relationship of between EBV & CMV infections with some clinicopathological factors which were involved in this study. The present study was designed as a prospective research with (90) serum samples as (45) specimens from hypertensive patients
Determination of the Cytomegalovirus (CMV) infection Role with the Disturbances of Immunoglobulin E (IgE) and Interleukin-33 (IL-33) Concentrations in the Pathogenesis of Asthma and Atherosclerosis in a Sample of Iraqi Patients,
Background: The previous laboratory investigations confirmed local polio case was informed on 28 th January 2000 and another two wild polio cases were reported from Resafa \ Baghdad province in 2014. The date of onset of these cases were February and April 2014 and both cases were connected to 2013 of Syria outbreak. Objective:To evaluate the knowledge and attitudes levels towards polio vaccination among staff of Technical Institute-AL-Suwaira. Patients and Methods: A study of cross-sectional design consisted of 170 a selected samples of Technical Institute \ AL-Suwaira staff members. Collected during January 2018.The knowledge and attitudes levels estimated by using typical design of selfadministered questionnaire. Descriptive statistics were used to explain the results. Results: Over all, 170 participants reacted to the questionnaire by a response rate of 93.5%. All respondents established a good knowledge and positive attitudes levels to poliovirus vaccination. Mean knowledge score (built on11 knowledge questions) and mean attitude score (built on 10 attitudes statements) of participants about polio vaccine were 14.45±2.38 and 26.5±4.5 respectively. The mainstream of respondents agreed that all children should be taken the polio vaccine (88.2%), and the sterility concerns that associated with polio vaccines (14.1%). Television (n=126, 39%) and Internet (n = 66, 21%) were the main social media sources that used by staff members to educate and modify themselves about polio vaccination. Knowledge defects were recognized in the management issues and how to dealing with vaccines (45.9%), the incubation period of poliovirus infection (38.8%) and the consequences of the poliovirus infection (56.5%) on the victims. Conclusion: Staff members of Technical Institute \ AL-Suwaira showed a good knowledge and positive attitudes levels about polio vaccination. Even though the statistics are indicative of knowledge gaps of participants, further studies are needed to assess t hese levels for better education program against polio.
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