Synthesis of Aza-BODIPY Boron Difluoride PDT Agents to Promote Apoptosis in HeLa Cells. -Title compounds (I) are prepared (no yields given) and tested as agents in the photodynamic therapy in cancer treatment. All compounds except (VIIb) show a classic necrotic cell death profile. The ability of (VIIb) to induce apoptosis opposed to necrosis is the reason for the further examination of this compound. -(PRIEFER*, R.; GRIFFITHS, J. R.; LUDWIG, J. N.; SKELHORNE-GROSS, G.; GREENE, R. S.; Lett.
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