Background
Myofascial pain in masticatory muscles is one of the most common temporomandibular disorder. Nowadays, the most usable treatment methods are based on the muscle taut band cell membrane disruption, which releases the taut band.
Platelet‐rich plasma, made with PRGF Endoret® method, gives an opportunity to use platelet‐derived growth factors in treatment processes. It has been proven that platelet‐derived growth factors can relief pain and activate muscle regeneration.
Objective
To test a hypothesis that PRGF injections can be effective for treating myofascial pain in masticatory muscles.
Methods
Fifty adult patients participated in the study. Participants were randomly divided into two groups. The first group received 1‐mL lidocaine injections to trigger point in their masseter muscle. The second group of patients received 1‐mL PRGF injections. The patients' pain was measured by using visual analogue scale (VAS).
Result
Statistically significant difference in pain levels before the procedure and 4 weeks after it was found in both groups. There was no statistically significant difference between groups in pain levels before the procedure (P = .063) and 2 weeks after it (P = .123); however, statistically significant difference was noticed 4 weeks after the procedure (P < .001). Four weeks after the procedure, patients' average pain in lidocaine group was 3.4 on VAS, and it was 0.9 in PRGF group.
Conclusions
PRGF injections in masseter muscle affected by myofascial pain syndrome are an effective treatment method. PRGF injections more effectively relief myofascial pain in masseter muscle than lidocaine injections.
Persistent idiopathic facial pain (PIFP) is an enigmatic condition presenting with variable features. Psychiatric comorbidities are speculated to influence PIFP.
In this study, the authors evaluated patients with PIFP through the hospital anxiety and depression scale, facial expression analysis, and electrodermal activity.
A total of 67 respondents enrolled as the experimental group and 28 participants as the control group. Pain scores were higher in the experimental group (5.24; SD 2.349)
P
< 0.001 depression (5.58 (SD 3.766) versus 3.07 (SD 2.418),
P
= 0.002) and anxiety scores (9.78 (SD 4.923) versus 6.75 (SD 4.097)
P
= 0.007) were higher in the experimental group. The experimental group expressed more negative episodes (
P
= 0.024); Electrodermal Activity data in terms of peaks/min (
P
= 0.872) and average peak amplitude (
P
= 0.168) were not significantly different between the groups.
It may be concluded that pain levels may be influenced by psychiatric comorbidity as PIFP patients showed insignificant physiological response to pain.
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