Purpose: To compare intubating conditions and postoperative myalgias in outpatients after intubation with propofol/alfentanil compared with propofol/alfentanil/succinylcholine with and without precurarisation with d-tubocurarine.Methods: 144 ASA I -II ambulatory patients for dental extraction under anesthesia were studied. Subjects received either 3mg d-tubocurarine (Group II) or saline (Groups I, III) iv prior to induction of anesthesia with 20 µg·kg -1 alfentanil and 2.5 mg·kg propofol followed by 1.5 mg·kg -1 succinylcholine (II and III) or saline 0.9% (I) for muscle relaxation. The ease of airway management and the postoperative incidence, severity and distribution of muscle pains were examined.Results: Intubation was successful in all patients and there were no differences in jaw mobility, ease of bag-mask ventilation, visualization of the vocal cords or cord position. Limb movement was more common during intubation in Group I (37.5%) than in Group III (8.3%) or Group II (2%), P < 0.05. At home, VAS scores for myalgia were higher in Group III than in Group I and II. Neck myalgia was more common in Group III (72%) than in Groups II (44%) and I (41%), P < 0.05. Myalgias were also more common in Group III patients (P < 0.05).Conclusion: Acceptable intubating conditions were achieved with propofol and alfentanil alone. Succinylcholine reduced limb movement during intubation but was associated with postoperative myalgias for up to five days. Precurarisation with tubocurarine reduced the severity of succinylcholine myalgia. Résultats : L'intubation a réussi chez tous les patients. Il n'y a pas eu de différence concernant la mobilité de la mâchoire, la facilité de ventilation au masque, la visualisation des cordes vocales ou leur position. Les mouvements des membres étaient plus fréquents à l'intubation chez les patients du Groupe I (37,5 %) que des Groupes III (8,3 %) et II (2 %), P < 0,05. Après le congé, les scores de myalgie à l'EVA étaient plus hauts dans le Groupe III que dans les Groupes I et II. La myalgie du cou a été plus fréquente dans le Groupe III (72 %) que dans les Groupes II (44 %) et I (41 %), P < 0,05. Les myalgies ont été aussi plus fréquentes dans le Groupe III ( P < 0,05).Conclusion : L'emploi de propofol / alfentanil seul a permis des conditions d'intubation acceptables. La succinylcholine a diminué les mouvements des membres pendant l'intubation, mais a été associée à des myalgies jusqu'à cinq jours après l'opération. La précurarisation avec la tubocurarine a réduit la sévérité de la myalgie reliée à la succinylcholine.
The steady‐flow behavior of five samples of branched poly(vinyl acetate) has been studied with the Weissenberg rheogoniometer. The branching densities and molecular weight distributions were known from an analysis of the polymerization kinetics. Measurements were made on concentrated diethyl phthalate solutions (0.170 and 0.225 g/ml) at temperatures of 30 and 70°C. The viscosities of all solutions at zero shear rate were less than of solutions of linear poly(vinyl acetate) with the same weight‐average molecular weight. The amount of decrease was in excellent agreement with Bueche's theory of melt viscosity in branched systems. The viscosity versus shear rate curves were surprisingly independent of molecular weight distribution, the data from all samples being superimposable on the same master curve. Relaxation times derived independently from the viscosity behavior and the normal stress data were of similar magnitude and always close to the Rouse relaxation time of each solution.
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