TF was an effective treatment for patients with GERD symptoms, particularly in those with persistent regurgitation despite PPI therapy, based on evaluation 6 months after the procedure. Clinicaltrials.gov no: NCT01136980.
We have performed a comprehensive dosimetric characterization of the Oncura model 6711 125I seed using both experimental [LiF thermoluminscent dosimetry (TLD)] and theoretical (Monte Carlo photon transport) methods. In addition to determining the dosimetric parameters of the 6711, this report quantified: (1) the angular dependence of LiF TLD energy response functions for both point and volume detectors in water, poly(methylmethacrylate), and solid water media; and (2) the contribution of underlying geometric uncertainties to the overall uncertainty of Monte Carlo derived dosimetric parameters according to the National Institute of Standards and Technology Report 1297 methodology. The theoretical value for the dose rate constant in water was 0.942 cGy U(-1) h(-1)+/-1.76% [combined standard uncertainty (CSU) with coverage factor k=1] and the experimental value was 0.971 cGy U(-1) h(-1)+/-6.1%. Agreement between experimental and theoretical radial dose function values was well within the k= 1 CSU, while agreement between experimental and theoretical anisotropy function values was within the k= 1 CSU only after incorporating the use of polar angle-dependent energy response functions. The angular dependence of the relative energy response was found to have a complex and significant dependence on measurement medium and internal geometry of the source.
The major predictors of morbidity after an esophagectomy are the patient factors of diabetes, dyspnea, peripheral vascular disease, and cerebrovascular accident while the peri-operative factors are pre-operative international normalized ratio, contaminated wound classification, and American Society of Anesthesiologists class. Similarly, the major predictors of mortality are diabetes, dyspnea, and age for patient factors and contaminated wound classification for peri-operative factors.
These data show an increase in the percentage of cholecystectomies performed laparoscopically over the years under study and an associated low mortality rate. In contrast, although the number of bile duct injuries appears to be decreasing, these procedures continue to be associated with a significant mortality rate.
Hiatal hernias are commonly incidental findings. When hernias become symptomatic or have reflux disease, an operative repair is required. A minimally invasive approach is safe and has improved outcomes.
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