SYNOPSISThe clinical and pathological findings in a 59-year-old woman with a primary malignant lymphoma of the corpus uteri are described. There was a period of eight months between detection of the uterine lesion and evidence of disease elsewhere in the body. The patient died of disseminated lymphoma, and the distribution of secondary deposits were suggestive of spread via the right ovarian-uterine venous system.
This is the fourth documented case of subcutaneous involvement by Whipple's disease. One should consider the possibility of Whipple's disease in any patient who presents with symptoms compatible with that condition who demonstrates septal panniculitis with a large amount of foamy histiocytes.
Summary
A case of bilateral pulmonary agenesis and the first of total tracheopulmonary agenesis, is reported. In addition to absence of the lower portion of the larynx, trachea and lungs, there were several cardiac abnormalities, including a common atrio‐ventricular valve, persistent ostium primum, interventricular septa1 defect, truncus arteriosus and absence of both pulmonary trunk and arteries. Additional malformations present included a persistent left superior vena cava, left azygos vein, absence of the spleen, gastric hypoplasia and a hemivertebra. The embryology of the defects in the present case is discussed with particular reference to their time of onset and causation and the important findings compared with those of previously published cases. It is suggested that inception of splenic development may occur earlier than has previously been postulated.
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