The presence of caffeine or human Pharmaceuticals in ground water with elevated nitrate concentrations can provide a clear, unambiguous indication that domestic waste water is a source of some of the nitrate. Water from domestic, public supply, and monitoring wells in three communities near Reno, Nevada, was sampled to test if caffeine or Pharmaceuticals are common, persistent, and mobile enough in the environment that they can be detected in nitrate‐contaminated ground water and, thus, can be useful indicators of recharge from domestic waste water. Results of this study indicate that these compounds can be used as indicators of recharge from domestic waste water, although their usefulness is limited because caffeine is apparently nonconservative and the presence of prescription Pharmaceuticals is unpredictable. The absence of caffeine or Pharmaceuticals in ground water with elevated nitrate concentrations does not demonstrate that the aquifer is free of waste water contamination. Caffeine was detected in ground water samples at concentrations up to 0.23 μg/L. The human Pharmaceuticals chlorpropamide, phensuximide, and carbamazepine also were detected in some samples.

Chronic exposure to arsenic (As) by drinking shallow groundwater causes widespread disease in Bangladesh and neighboring countries. The release of As naturally present in sediment to groundwater has been linked to the reductive dissolution of iron oxides coupled to the microbial respiration of organic carbon (OC). The source of OC driving this microbial reduction-carbon deposited with the sediments or exogenous carbon transported by groundwater-is still debated despite its importance in regulating aquifer redox status and groundwater As levels. Here, we used the radiocarbon ( 14 C) signature of microbial DNA isolated from groundwater samples to determine the relative importance of surface and sediment-derived OC. Three DNA samples collected from the shallow, high-As aquifer and one sample from the underlying, low-As aquifer were consistently younger than the total sediment carbon, by as much as several thousand years. This difference and the dominance of heterotrophic microorganisms implies that younger, surface-derived OC is advected within the aquifer, albeit more slowly than groundwater, and represents a critical pool of OC for aquifer microbial communities. The vertical profile shows that downward transport of dissolved OC is occurring on anthropogenic timescales, but bomb 14 C-labeled dissolved OC has not yet accumulated in DNA and is not fueling reduction. These results indicate that advected OC controls aquifer redox status and confirm that As release is a natural process that predates human perturbations to groundwater flow. Anthropogenic perturbations, however, could affect groundwater redox conditions and As levels in the future.A quifer redox status is a major factor affecting groundwater composition and its suitability for human consumption. The most egregious example is the dire health impact of elevated levels of arsenic (As) in groundwater drawn with inexpensive handpumped tube wells by more than 100 million villagers across South, Southeast, and East Asia (1, 2). Aquifer redox status is largely controlled by microbial respiration of organic carbon (OC) coupled to the utilization of terminal electron acceptors. Reduction of iron (Fe) oxides containing As coupled with the oxidation of OC is the dominant process causing the accumulation of As in groundwater (1), but there is no consensus on the source of OC that fuels these transformations. Such information is critical to understanding subsurface carbon cycling, redox reactions, and the vulnerability of groundwater aquifers to perturbation.Human perturbations have long been suggested to exacerbate the problem of elevated As in groundwater in several ways. Given the connectivity between contaminated surface waters and aquifers, widespread pumping could redistribute As from the surface to depth (3, 4) or between aquifers (5). This pumping could potentially also deliver reactive OC from ponds and latrines to depth, causing microbial reduction and As release (3, 4). Fluorescent spectra of dissolved organic carbon (DOC), correlations between sedimentary ...

Older men (n = 12) and women (n = 18) 65-80 years of age completed 12 weeks of exercise and took either a placebo or resveratrol (RSV) (500 mg/d) to test the hypothesis that RSV treatment combined with exercise would increase mitochondrial density, muscle fatigue resistance, and cardiovascular function more than exercise alone. Contrary to our hypothesis, aerobic and resistance exercise coupled with RSV treatment did not reduce cardiovascular risk further than exercise alone. However, exercise added to RSV treatment improved the indices of mitochondrial density, and muscle fatigue resistance more than placebo and exercise treatments. In addition, subjects that were treated with RSV had an increase in knee extensor muscle peak torque (8%), average peak torque (14%), and power (14%) after training, whereas exercise did not increase these parameters in the placebo-treated older subjects. Furthermore, exercise combined with RSV significantly improved mean fiber area and total myonuclei by 45.3% and 20%, respectively, in muscle fibers from the vastus lateralis of older subjects. Together, these data indicate a novel anabolic role of RSV in exercise-induced adaptations of older persons and this suggests that RSV combined with exercise might provide a better approach for reversing sarcopenia than exercise alone.

Writers and practitioners in dementia care have invoked personhood to offer potential for preserving the agency of people living with dementia. In this context we use personhood to explore how relationships bring agentive potential to experience-centered design through a cocreative, design-led inquiry with Gillian, a woman living with dementia, and John her husband. We designed bespoke probes to empathically engage the couple in the design of both jewellery and digital jewellery to support Gillian's personhood. Our design activity addressed the relationships involved in the context of Gillian's family life and the progression of her illness and how they could be mediated technologically. Reminiscence became, through Gillian and John's own hands, acts of sense making and legacy. The process of design became the way of conducting the inquiry and the designed artifacts became ways of posing questions to make sense of our experiences together.

The physical mechanisms by which the Reynolds shear stress is produced from dynamically evolving vortical structures in the wall region of a direct numerical simulation of turbulent channel flow are explored. The complete set of quasistreamwise vortices are systematically located and tracked through the flow by the locus of the points of intersection of their centres of rotation with the (y , z) numerical grid planes. This approach assures positive identification of vortices of widely differing strengths, including those whose amplitude changes significantly in time. The process of vortex regeneration, and the means by which vortices grow, distort and interact over time are noted. Ensembles of particle paths arriving on fixed planes in the flow are used to represent the physical processes of displacement and acceleration transport (Bernard & Handler 1990a) from which the Reynolds stress is produced. By interweaving the most dynamically significant of the particle paths with the evolving vortical structures, the dynamical role of the vortices in producing Reynolds stress is exposed. This is found to include ejections of low-speed fluid particles by convecting structures and the acceleration and deceleration of fluid particles in the cores of vortices. Sweep dominated Reynolds stress close to the wall appears to be a manifestation of the regeneration process by which new vortices are created in the flow.

Aver age chemical and isotopic compositions of water from wells and spring in southern Nevada and so utheastern California, between latitud es 35 a nd 38 degrees north and longitudes 114 and 117 degrees east.

Abstract:Despite record investment in diversity infrastructure, racial inequality persists in higher education. This article examines how through a case study of diversity's articulation process: how diversity is defined, organized, and implemented within an American public flagship university.My findings reveal what I characterize as a diversity regime: a set of meanings and practices that institutionalize a benign commitment to diversity, and in doing so obscure, entrench, and even intensify existing racial inequality by failing to make fundamental changes in how power, resources, and opportunities are distributed. My concept of a diversity regime helps explain how and why organizational commitments to multiculturalism and diversity often fall short in practice. The concept of a diversity regime also helps us better understand the underlying processes that perpetuate racial inequality.https://mc.manuscriptcentral.com/scu Social Currents While these shifts suggest diversity has been successful, social scientific research shows a mixed bag. Though racially diverse campuses may produce long-term psychological and social gains for students, some research finds whites receive the greatest benefits while the effects are weakest for minorities (Antonio et al. 2004;Hurtado et al. 2015). Other research finds that even at universities with commitments to diversity, minorities experience isolation, alienation, and daily micro-aggressions (Swim et al. 2003). Despite increases in minority student enrollment, minority faculty remain woefully underrepresented and experience similar treatment as minority students (Fenwick and Swygert 2015; Pittman 2012).Recent high-profile incidents across several college campuses suggest diversity's success is misleading, at best. Colleges and universities remain sites where varying degrees of racial poorly': when minority representation remains little more than tokenism, when racial and gendered wage-gaps persist, or when decision-making remains concentrated within the hands of a relatively small group of elite, white men. Yet, the 'going' aspect of 'going poorly' receives little attention. We need to do more than document poor results if we want to better understand the persistence of racial inequality in an era saturated by diversity discourse. We need to attend to the processes that produce them (see Schwalbe et al. 2000).In this article I make use of more than two years of ethnographic fieldwork to describe and analyze diversity's articulation at Diversity University (DU), a public, flagship university in the American South. My findings reveal what I characterize as a diversity regime: a set of meanings and practices that institutionalize a benign commitment to diversity, and in doing so obscure, entrench, and even intensify existing racial inequality by failing to make fundamental changes in how power, resources, and opportunities are distributed. I identify three key components of DU's diversity regime. Condensation illustrates how diversity's definitional work disassociates it from ...

The implementation of a simple, low-cost oral care protocol in the surgical intensive care unit led to a significantly decreased risk of acquiring ventilator-associated pneumonia.