A COVID-19 outbreak occurred in the Diamond Princess cruise ship and we sampled environmental surfaces after passengers and crews vacated the cabins. SARS-CoV-2 RNA was detected from 58 out of 601 samples (10%) from case-cabins 1-17 days after the cabins were vacated, but not from non-case-cabins. There was no difference in the detection proportion between cabins for symptomatic (15%, 28/189, Cq: 29.79-38.86) and asymptomatic cases (21%, 28/131, Cq: 26.21-38.99). No SARS-CoV-2 virus was isolated from any of the samples. Transmission risk of SARS-CoV-2 from symptomatic and asymptomatic patients may be similar and environmental surfaces could be involved in viral transmission.

The incidence of shoulder injuries in the paediatric athletic population continues to increase with increased participation particularly in throwing and overhead sports. While soft tissue injuries can occur, the physis remains the weak link and site of injury in many cases. Injury prevention targets proper throwing mechanics and the avoidance of overuse injuries by monitoring the amount of training and number of throws these young athletes are exposed to.

These data find that LSD and PcM use occurs primarily in adolescents and young adults, who experience mild to moderate adverse effects. Serious effects are infrequent but can occur. While most LSD and PcM users require only emergency department management, LSD use is more likely to require medical admission.

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Purpose Identify if publication of the 2010 drug safety communication (DSC) regarding benzonatate was associated with a decrease in the incidence of severe benzonatate poisonings reported to United States poison centers. Methods This retrospective database study utilized the National Poison Data System to compare the incidence of severe benzonatate poisonings before and after the publication of a drug safety communication. We utilized interrupted time series analysis to compare 2000‐2010 (pre‐DSC) to 2012‐2019 (post‐DSC). Results There were 18 619 benzonatate exposures reported to US poison centers during the time period covered and 11 554 exposures were included. There was an increase in exposures throughout the time period. There was no difference in the incidence of severe outcomes in the two time periods. In the pre‐DSC era, rates of severe outcomes increased by 0.4% per year followed by an immediate non‐significant drop of 2.9% in incidence of severe outcomes (P = .15). Finally, the slope of severe outcomes in the post‐DSC era showed an increase of 0.3% per year, which was not significantly different from the pre‐DSC era (P = .78). Conclusion Publication of a Drug Safety Communication regarding the risks of benzonatate did not result in a decrease in the proportion of severe benzonatate poisoning reported to US poison centers. Deaths and other severe outcomes continued to occur at a similar rate after the publication.

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