Neuropsychological variables and urine cannabinoid metabolites were evaluated in ten subjects born, raised, and educated in the United States and having histories of heavy or prolonged use of cannabis. No impairment of cognitive function was found. Cannabinoid metabolites in excess of 50 nanograms per milliliter were present in the ten urine samples. The tetrahydrocannabinol content of cannabis exceeded 8.0%.
Psychopathology following epilepsy neurosurgery is a significant risk. Treatment modalities have not been addressed in the literature. As disproportionately elevated suicide rates have been reported, it is critical to treat aggressively any psychiatric illness wherein suicidal ideation is a key component. This case reports the safe utilization of electroconvulsive therapy (ECT) for intractable depression following epilepsy neurosurgery (24 references).
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