Patients with adrenal metastases from melanoma, either isolated or with a limited number of additional metastases, may benefit from surgical resection if all visible disease can be removed. Patients with unresectable extra-adrenal disease achieve no survival benefit from adrenalectomy.

In principle, the ability to detect a luminance increment is lowered when there is uncertainty for its spatial location. Frequency-of-seeing curves were generated for small foveal targets. When fixed in space the target's detectability was more than 10 times higher than when it could occur at one of 140 locations.

No abstract