ISTRN 90646644.

Background: To assess the ability of the Chromatest in investigating diabetic maculopathy.

Purpose To estimate the prevalence of posterior embryotoxon (PE) in the general ophthalmic clinic and to identify any features of PE that suggest that it is pathological rather than physiological. Methods Over 700 consecutive patients of all ages were examined with the slit lamp during their routine eye clinic appointment. Patients with posterior embryotoxon were invited to return for full ocular examination including keratometry, corneal topography, and gonioscopy. Results In all, 49 out of 723 patients were found to have PE. This gives a prevalence of 6.8% with an age range of 18 months to 95 years. There was a higher prevalence in the younger age group of 22.5% (age range 18 months to 20 years) compared to 5.9% in the older age range (21-95 years).A total of 29 patients with PE returned for further examination. Six patients had glaucoma (two with Axenfeld's syndrome and one with aniridia), and one had ocular hypertension. In all, 20 patients had bilateral PE on slit-lamp examination, which increased to 24 with gonioscopy. The majority of the PE was seen temporally (97.9%) and limited to a few clock hours. Gonioscopy showed that eight patients with PE had associated inferior pigmentation of schwalbes line. Conclusion This large series found the prevalence of PE the general ophthalmic clinic to be 6.8%. Its presence should prompt careful anterior segment examination, including gonioscopy, to identify any associated abnormalities that may carry a risk of glaucoma. Children should also be assessed for any associated systemic or genetic abnormality.

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The POCOman is an effective, user-friendly system for quantifying PCO. It can be obtained for free and has advantages over other methods.

We report an unusual case of two co-existent and opposing retinal vein occlusions where obstruction was thought to occur at the trunk of the central retinal vein at or near the level of the lamina cribrosa, a site usually associated with the formation of hemi-vein or central retinal vein occlusion. This had occurred as a result of tortuous vasculature at the optic disc. This unusual case lends weight to previously suggested hypotheses of retinal vein occlusion.

Jaheed Khan and colleagues discuss the barriers in diagnosing eye disease and point out potential solutions to overcome these problems

Abstract